Early-Onset Colorectal Cancer Patients Too Young for Screening
1 other identifier
observational
100
1 country
1
Brief Summary
This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Jan 2020
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
January 31, 2020
CompletedFirst Submitted
Initial submission to the registry
March 18, 2026
CompletedFirst Posted
Study publicly available on registry
April 30, 2026
CompletedPrimary Completion
Last participant's last visit for primary outcome
January 1, 2027
ExpectedStudy Completion
Last participant's last visit for all outcomes
January 1, 2028
April 30, 2026
January 1, 2026
6.9 years
March 18, 2026
April 27, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
Age
colorectal cancer (CRC) patients younger than 35 years and comparing them against CRC patients older than 35 years of age.
20 years
Study Arms (1)
colorectal cancer (CRC) patients younger than 35
The hypothesis is that patients younger than 35 years of age with CRC will present with more advanced disease at diagnosis but will have longer survival overall through more aggressive therapy.
Interventions
CRC is a disease that is often associated with older adults (\<50 years). CRC remains the second most common cause of cancer death in males and the third most common cancer death in women. Despite this, CRC incidence has steadily declined in older adults; however, there is a concerning rise of incidence of colorectal cancer in young patients. The incidence of CRC in men and women under the age of 50 steadily increased 2.1 percent per year from 1992 through 2012.
Eligibility Criteria
This is a population-based retrospective study using the Surveillance, Epidemiology, and End Results (SEER) registry and National Cancer Data Base (NCDB) to look at colorectal cancer (CRC) patients younger than 35 and comparing them against CRC patients older than 35 years of age.
You may qualify if:
- Colorectal cancer
You may not qualify if:
- No Colorectal cancer
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Methodist Dallas Medical Center- Clinical Research Institute
Dallas, Texas, 75203, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Rohan Jeyarajah, MD
Methodist Health System
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
March 18, 2026
First Posted
April 30, 2026
Study Start
January 31, 2020
Primary Completion (Estimated)
January 1, 2027
Study Completion (Estimated)
January 1, 2028
Last Updated
April 30, 2026
Record last verified: 2026-01
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- STUDY PROTOCOL
- Time Frame
- Not mentioned in protocol.
- Access Criteria
- Not mentioned in protocol.
The data attained will be de-identified prior to sharing via presentation and/or publication in relevant research mediums.