Posterior Quadratus Lumborum Block Using 0.125% Versus 0.25% Bupivacaine for Analgesia in Children Undergoing LPEC
Comparison of Analgesic Efficiency in Laparoscopic Percutaneous Extraperitoneal Closure for Pediatric Inguinal Hernia and Hydrocele Provided by Ultrasound Guided Posterior Quadratus Lumborum Block Using Between 0.125% and 0.25% Bupivacaine
1 other identifier
interventional
50
1 country
1
Brief Summary
The aim of the present study is to evaluate and compare the analgesic efficiency of the difference concentration between 0.125% and 0.25% bupivacaine provided by ultrasound guided posterior quadratus lumborum block undergoing LPEC in children
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable postoperative-pain
Started Aug 2021
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
July 9, 2021
CompletedFirst Posted
Study publicly available on registry
August 10, 2021
CompletedStudy Start
First participant enrolled
August 15, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 31, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
June 30, 2022
CompletedAugust 10, 2021
August 1, 2021
10 months
July 9, 2021
August 1, 2021
Conditions
Outcome Measures
Primary Outcomes (1)
Quality of postoperative analgesia
Postoperative pain score as CHEOPs SCORE
24 hours after surgery
Secondary Outcomes (1)
Incidence of complications
12 hours after surgery
Study Arms (2)
ROUTINE DRUG - CONCENTRATION QLB
ACTIVE COMPARATORThe patients will receive bilateral posterior quadratus lumborum block using 0.25% bupivacaine 0.4 ml/kg. in each side.
ALTERNATIVE DRUG - CONCENTRATION QLB
ACTIVE COMPARATORThe patients will receive bilateral posterior quadratus lumborum block using 0.125% bupivacaine 0.4 ml/kg. in each side.
Interventions
Analgesic efficiency comparison between two concentration of bupivacaine hydrochloride using for posterior quadratus lumborum block in LPEC
Eligibility Criteria
You may qualify if:
- Children scheduled for laparoscopic percutaneous extraperitoneal closure(LPEC) for pediatric inguinal hernia and hydrocele
- ASA I-II physical status patients
- Complete inform consent for intervention
You may not qualify if:
- Contraindication for regional anesthesia
- Sensitive to local anesthetic agent, opioid or acetaminophen
- Previous history of abdominal surgery
- History of neuromuscular disease
- G6PD deficiency
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Queen Sirikit National Institute of Child Health
Ratchathewi, Bangkok, 10400, Thailand
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
SUWITCHA TAMRONGCHOTE, MD
Queen Sirikit National Institute of Child Health (QSNICH)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- QUADRUPLE
- Who Masked
- PARTICIPANT, CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER GOV
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Queen Sirikit National Institute of Child Health
Study Record Dates
First Submitted
July 9, 2021
First Posted
August 10, 2021
Study Start
August 15, 2021
Primary Completion
May 31, 2022
Study Completion
June 30, 2022
Last Updated
August 10, 2021
Record last verified: 2021-08