The Chinese STEMI PPCI Registry (CSPR)

NCT04996901 | Completed DMC

• 1 other identifier: 958374
• Study Type: observational
• Target: 5,594
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to develop a risk score to predict the risks of in-hospital major adverse cardiac events in ST-segment elevation myocardial infarction patients treated by primary percutaneous coronary intervention.

Conditions

ST-segment Elevation Myocardial Infarction (STEMI)

Outcome Measures

Primary Outcomes (3)

• in-hospital acute de novo heart failure

  Killip class ≥II

  in-hospital outcome, until discharge

• cardiogenic shock

  according to the universal definition

  in-hospital outcome, until discharge

• death

  according to the universal definition

  in-hospital outcome, until discharge

Study Arms (2)

derivation cohort

Data from Renmin Hospital of Wuhan University, The First College of Clinical Medical Science, China Three Gorges University, The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture, Xiangyang No.1 People's Hospital，and Wuhan Third Hospital will be used as a derivation cohort.

Other: no intervention

validation cohort

Data from The First Affiliated Hospital of Dalian Medical University and Jiangxi Provincial People's Hopital will be used as a derivation cohort.

Other: no intervention

Interventions

no intervention OTHER

no intervention

derivation cohort; validation cohort

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All patients with STEMI were treated by primary percutaneous coronary intervention at 7 large centers from central China.

You may qualify if:

• Age≥18
• ST-segment elevation myocardial infarction was defined according to the universal definition of myocardial infarction
• STEMI treated by pPCI

You may not qualify if:

• Patient with heart failure in admission
• STEMI with symptom-onset-to-balloon time\>24h
• pPCI was not successful or only underwent coronary angiography
• Killip class ≥II in admission

Sponsors & Collaborators

• Renmin Hospital of Wuhan University: lead
• The First College of Clinical Medical Science, China Three Gorges University: collaborator
• The First Affiliated Hospital of Dalian Medical University: collaborator
• Jiangxi Provincial People's Hopital: collaborator
• The Central Hospital of Enshi Tujia And Miao Autonomous Prefecture: collaborator
• Xiangyang No.1 People's Hospital: collaborator
• Wuhan Third Hospital: collaborator

Study Sites (1)

Renmin Hospital of Wuhan university

Wuhan, Hubei, 430000, China

Location

Related Publications (4)

• Xu J, Luo D, Lei Y, Hu Z, Tian H, Chen X, Zhou W, Li M, Liu S, Jin X, Wang Y, Zhang B, Zhou Q, Chen J. Correlation between abnormal microvascular perfusion and quantitative flow ratio after primary PCI in patients with STEMI. Int J Cardiol. 2025 Mar 1;422:132949. doi: 10.1016/j.ijcard.2024.132949. Epub 2024 Dec 31.

  PMID: 39746473 DERIVED

• Wang H, Yang Y, Zeng P, Huang R, Cai X, Shao L, Liu F, Lei Y, Li D, Fan Z, Yang J, Zhang J, Yang J. Association between Systemic Immune-Inflammation Index (SII) and New-Onset In-Hospital Heart Failure in Patients with STEMI after Primary PCI. Rev Cardiovasc Med. 2024 Oct 24;25(10):382. doi: 10.31083/j.rcm2510382. eCollection 2024 Oct.

  PMID: 39484131 DERIVED

• Hu Z, Luo D, Zhou WJ, Xu CW, Chen XZ, Zhang BF, Jin X, Wang Y, Zhang J, Wu H, Liu FY, Lei YH, Li DS, Cai XY, Jiang H, Chen J. Association between admission blood pressure and spontaneous reperfusion and long-term prognosis in STEMI patients: an observational and multicenter study. BMC Cardiovasc Disord. 2024 Sep 18;24(1):500. doi: 10.1186/s12872-024-04168-4.

  PMID: 39294617 DERIVED

• Luo D, Huang R, Wang X, Zhang J, Cai X, Liu F, Lei Y, Li D, Zhou W, Xu C, Huang B, Jiang H, Chen J. INTRA-AORTIC BALLOON PUMP REDUCES 30-DAY MORTALITY IN EARLY-STAGE CARDIOGENIC SHOCK COMPLICATING ACUTE MYOCARDIAL INFARCTION ACCORDING TO SCAI CLASSIFICATION. Shock. 2023 Sep 1;60(3):385-391. doi: 10.1097/SHK.0000000000002184. Epub 2023 Aug 4.

  PMID: 37548623 DERIVED

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Condition Hierarchy (Ancestors)

Myocardial Infarction; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Study Officials

• Liwei Cheng

  Renmin Hospital of Wuhan University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 27, 2021
• First Posted: August 9, 2021
• Study Start: May 22, 2021
• Primary Completion: December 5, 2021
• Study Completion: December 5, 2021
• Last Updated: December 20, 2021

Record last verified: 2021-12

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)