The Prognostic Value of Anion Gap in Predicting Major Adverse Cardiovascular Events Among Patients With ST-Segment Elevation Myocardial Infarction

NCT06586424 | Recruiting

• 1 other identifier: Undip_Kardio 2
• Study Type: observational
• Target: 80
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the prognostic value of the anion gap in predicting major adverse cardiovascular events among patients with ST-segment elevation myocardial infarction. Researchers will collect information based on hospital registry as secondary data of in patient who had diagnosed as ST-segment elevation myocardial infarction and underwent primary percutaneous coronary intervention. The data consist of demographic data, clinical presentation, laboratory, and angiography result were collected from hospital registry by reviewing medical record. Then, the data was analyzed by using IBM SPSS Statistics v26.

Conditions

ST-segment Elevation Myocardial Infarction (STEMI)

Keywords

anion gap; major adverse cardiovascular events; st-segment elevation myocardial infarction

Outcome Measures

Primary Outcomes (1)

• Major Adverse Cardiovascular Events (MACE)

  During hospitalization, up to 1 weeks

Secondary Outcomes (6)

• Incidence of mortality

  During hospitalization, up to 1 weeks

• Incidence of reinfarction

  During hospitalization, up to 1 weeks

• Incidence of stroke

  During hospitalization, up to 1 weeks

• Incidence of lethal arrhythmia

  During hospitalization, up to 1 weeks

• Incidence of acute lung oedema

  During hospitalization, up to 1 weeks

Study Arms (1)

MACE group

Patient with STEMI who suffered major adverse cardiovascular events (MACE) after underwent primary percutaneous coronary intervention (PPCI)

Diagnostic Test: Anion gap

Interventions

Anion gap DIAGNOSTIC_TEST

Patient was taken blood examination before PPCI

MACE group

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patient with ST-segment elevation myocardial infarction who underwent PPCI

You may qualify if:

• Adults with 18 - 70 years old with diagnosis of STEMI who underwent PPCI

You may not qualify if:

• History of heart failure due to any causes
• Cardiogenic shock before PPCI
• Any infection at the time of presentation
• Pregnant woman
• Other causes of high anion gap levels such as chronic kidney disease, metabolic acidosis, etc

Sponsors & Collaborators

• Universitas Diponegoro: lead

Study Sites (1)

Dr. Kariadi Central General Hospital

Semarang, Central of Java, Indonesia

RECRUITING

MeSH Terms

Conditions

ST Elevation Myocardial Infarction

Interventions

Acid-Base Equilibrium

Condition Hierarchy (Ancestors)

Myocardial Infarction; Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases; Infarction; Ischemia; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Necrosis

Intervention Hierarchy (Ancestors)

Biochemical Phenomena; Chemical Phenomena; Hydrogen-Ion Concentration; Metabolism; Homeostasis; Physiological Phenomena; Blood Physiological Phenomena; Circulatory and Respiratory Physiological Phenomena

Central Study Contacts

Leo Deddy Pradipta

CONTACT

+6281316499074; dancingdeagle@gmail.com

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 7 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator; Former of Head of Department of Cardiovascular Medicine Faculty of Medicine Universitas Diponegoro

Study Record Dates

• First Submitted: August 31, 2024
• First Posted: September 19, 2024
• Study Start: January 1, 2024
• Primary Completion: June 30, 2024
• Study Completion: October 5, 2024
• Last Updated: September 19, 2024

Record last verified: 2024-09

Data Sharing

• IPD Sharing: Will not share

Locations

ID (1)