Examination of Acute Effects of Different Intensity Respiratory Muscle Training on Respiratory Muscle Activations

NCT04974788 | Unknown

• 1 other identifier: AIBU-FTR-CT-03
• Study Type: interventional
• Target: 20
• Locations: 0 countries
• Sites: N/A

Brief Summary

It has been observed in the literature that respiratory muscle electromyography activations at certain threshold loads have been examined in individuals with chronic obstructive pulmonary disease. However, no study has been found in the literature examining the acute effects of respiratory muscle training given at low, medium and high threshold loads on respiratory muscle activations. With this planned study, it is aimed to examine the electromyography activations of respiratory muscles before and after respiratory muscle training and to contribute to the literature by comparing the acute effects of respiratory muscle training applied at low, medium and high intensity on respiratory muscle electromyography activations.

Conditions

Chronic Obstructive Pulmonary Disease

Keywords

Chronic Obstructive Pulmonary Disease; Surface EMG; Ventilation; Respiratory Muscle Training

Outcome Measures

Primary Outcomes (1)

• Surface Electromyography (EMG)

  Activation of respiratory muscles will be performed with a surface Electromyography (EMG) device. The measurement will be performed by placing Electromyography (EMG) electrodes on the motor points of the respiratory muscles. Increased respiratory muscle activations indicate that respiratory muscles are used more; The decrease in respiratory muscle activations indicates that the respiratory muscles are used less.

  45 minutes

Secondary Outcomes (5)

• Pulmonary Function Test

  10 minutes

• Measurement of Maximal Inspiratory Pressure

  5 minutes

• Chronic Obstructive Pulmonary Disease Assessment Test (CAT):

  5 minutes

• Modified Medical Research Council Dyspnea Scale:

  2 minutes

• Modified Borg Scale (MBS):

  2 minutes

Study Arms (3)

Low Intensity Respiratory Muscle Training Group

ACTIVE COMPARATOR

Low intensity respiratory muscle training will be applied to those with chronic obstructive pulmonary disease. Respiratory muscle training will be performed at 30% (low intensity) of the maximum inspiratory pressure, which indicates respiratory muscle strength.

Other: Low Intensity Respiratory Muscle Training

Medium Intensity Respiratory Muscle Training Group

ACTIVE COMPARATOR

Medium intensity respiratory muscle training will be applied to those with chronic obstructive pulmonary disease. Respiratory muscle training will be performed at 60% (medium intensity) of the maximum inspiratory pressure, which indicates respiratory muscle strength.

Other: Medium Intensity Respiratory Muscle Training

High Intensity Respiratory Muscle Training Group

ACTIVE COMPARATOR

High intensity respiratory muscle training will be applied to those with chronic obstructive pulmonary disease. Respiratory muscle training will be performed at 80% (high intensity) of the maximum inspiratory pressure, which indicates respiratory muscle strength.

Other: High Intensity Respiratory Muscle Training

Interventions

Low Intensity Respiratory Muscle Training OTHER

Respiratory muscle training will be performed at 30% (low intensity) of the maximum inspiratory pressure, which indicates respiratory muscle strength. The training will consist of 2 sessions in total; Each session will last 15 minutes. There will be a break of at least 30 minutes between training sessions.

Low Intensity Respiratory Muscle Training Group

Medium Intensity Respiratory Muscle Training OTHER

Respiratory muscle training will be performed at 60% (medium intensity) of the maximum inspiratory pressure, which indicates respiratory muscle strength. The training will consist of 2 sessions in total; Each session will last 15 minutes. There will be a break of at least 30 minutes between training sessions.

Medium Intensity Respiratory Muscle Training Group

High Intensity Respiratory Muscle Training OTHER

Respiratory muscle training will be performed at 80% (high intensity) of the maximum inspiratory pressure, which indicates respiratory muscle strength. The training will consist of 2 sessions in total; Each session will last 15 minutes. There will be a break of at least 30 minutes between training sessions.

High Intensity Respiratory Muscle Training Group

Eligibility Criteria

• Age: 40 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Individuals diagnosed with chronic obstructive pulmonary disease
• Be between the ages of 40-75
• No medication changes due to acute exacerbation for at least three weeks
• Be stable
• Volunteering to participate in research
• To cooperate
• Patients with written consent form
• Healthy individuals in a similar age range without a diagnosed disease and symptoms will be included

You may not qualify if:

• Those with a history of chronic obstructive pulmonary disease exacerbations
• Individuals with orthopedic disease
• Individuals with neurological disease
• Individuals with other co-existing lung and systemic diseases other than chronic obstructive pulmonary disease
• Those who have had major surgery in the past few months
• Individuals with a history of recurrent significant clinical infections
• Have cognitive problems
• Having had unstable angina,
• Previous Myocardial Infarction
• Individuals with severe congestive heart failure refractory to medical therapy, individuals with uncontrolled hypertension
• Individuals with cancer

Sponsors & Collaborators

• Abant Izzet Baysal University: lead

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Respiratory Aspiration

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Respiration Disorders

Central Study Contacts

Eylem TÜTÜN YÜMİN, Assoc. Prof.

CONTACT

05056763191; eylemtutun78@hotmail.com

Ceyhun TOPCUOĞLU, Res. Assist.

CONTACT

05356535137; ceyhuntopcuoglu1@gmail.com

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: Three groups with a conventional therapy

Study Record Dates

• First Submitted: July 9, 2021
• First Posted: July 23, 2021
• Study Start: June 30, 2023
• Primary Completion: July 30, 2023
• Study Completion: August 30, 2023
• Last Updated: October 28, 2022

Record last verified: 2022-10

Data Sharing

• IPD Sharing: Will not share