Clinical Related Study on Surgical Treatment of Knee Joint Meniscus Injury

NCT04962555 | Unknown

• 1 other identifier: IRB00006761-2015159
• Study Type: observational
• Target: 8,778
• Locations: 1 country
• Sites: 1

Brief Summary

Through the analysis of the data of 8094 patients with knee meniscus injury before December 31, 2008 and more patients with partial meniscus resection, subtotal resection and total resection, we can understand the gender difference and ratio of medial and lateral meniscus injuries. Differences, differences in locations, differences in tearing methods, differences in surgical methods, and the course of the disease affect the meniscus injury and surgical methods, and further affect the patient's knee degeneration imaging, accompanying cartilage injury, knee osteoarthritis, Partial resection, subtotal resection and meniscus regeneration after total resection, imaging and secondary arthroscopic exploration (Second-Look) were studied.

Conditions

Meniscus Injury

Outcome Measures

Primary Outcomes (6)

• Meniscus injury site

  Observe the meniscus injury site during the operation, which is divided into: medial and lateral anterior horn, medial and lateral body, medial and lateral posterior horn, medial and lateral disc.

  During operation

• Types of Meniscus Injury

  The types of meniscus injuries were observed during the operation, which were divided into longitudinal fissure, oblique fissure, spallation, radial fissure, and barrel shank tear.

  During operation

• Meniscus surgery method

  Meniscus surgery methods include: partial resection, subtotal resection, total resection, and suture.

  During operation

• Cartilage damage

  The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.

  During operation

• Cartilage damage

  Second-look after operation to observe whether the cartilage is damaged. The cartilage damage is evaluated as yes or no, where the cartilage surface is smooth and complete is defined as no, and the rest is defined as yes.

  7 years after surgery

• Meniscus regeneration

  Second-look after operation to observe whether the meniscus is regenerating. The Meniscus regeneration is evaluated as yes or no, in which the meniscus shape is complete and no tear is defined as yes, and other conditions are defined as no.

  7 years after surgery

Study Arms (4)

Meniscus Suture

The patient underwent meniscus suture surgery

Procedure: Meniscus Suture

Partial meniscus resection

The patient underwent partial meniscus resection

Procedure: Partial meniscus resection

Subtotal meniscus resection

The patient underwent Subtotal meniscus resection

Procedure: Subtotal meniscus resection

Complete meniscectomy

The patient underwent complete meniscectomy

Procedure: Complete meniscectomy

Interventions

Meniscus Suture PROCEDURE

Patients with knee joint meniscus injury undergoing meniscus suture

Meniscus Suture

Partial meniscus resection PROCEDURE

Patients with knee joint meniscus injury undergoing partial meniscus resection

Partial meniscus resection

Subtotal meniscus resection PROCEDURE

Patients with knee joint meniscus injury undergoing subtotal meniscus resection

Subtotal meniscus resection

Complete meniscectomy PROCEDURE

Patients with knee joint meniscus injury undergoing complete meniscectomy

Complete meniscectomy

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

8778 patients with meniscus injury who underwent surgery at the Institute of Sports Medicine of the Third Hospital of Peking University before December 31, 2008 and patients who underwent meniscus suture, partial resection, subtotal resection, or total resection afterwards

You may qualify if:

• Before December 31, 2008, patients who underwent surgery for meniscus injury in this institute and patients who underwent meniscus suture, partial resection, subtotal resection, and total resection.

Sponsors & Collaborators

• Peking University Third Hospital: lead

Study Sites (1)

Institute of Sports Medicine, Peking University Third Hospital

Beijing, Beijing Municipality, 100191, China

RECRUITING

Study Officials

• Jia-kuo Yu, Prof.

  Peking University Third Hospital

  STUDY CHAIR

Central Study Contacts

Jia-kuo Yu, Prof.

CONTACT

+86 13331031448; yujiakuo@126.com

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 27, 2021
• First Posted: July 15, 2021
• Study Start: August 1, 2016
• Primary Completion: October 1, 2022
• Study Completion: December 1, 2022
• Last Updated: July 15, 2021

Record last verified: 2021-06

Locations

CN (1)