Comparison of Isolated Meniscus Repair Versus Combined Meniscus Repair and Notch Microfracture: A Randomized Controlled Trial Evaluating Functional and Imaging Outcomes

NCT07609849 | Active Not Recruiting

• 1 other identifier: Meniscus Repair +microfracture
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to evaluate the efficacy of microfracture as an adjunctive augmentation technique in the repair of isolated meniscal tears. This will be achieved through comparing the functional and imaging outcomes of meniscus repair with notch microfracture in comparison with meniscal repair alone through a randomized control trial.

Conditions

Meniscus Injury

Keywords

Notch; Microfracture; Meniscus repair; meniscal repair; Lysholm; IKDC

Outcome Measures

Primary Outcomes (3)

• Lysholm

  Lysholm Evaluation Form

  6 months since surgery

• IKDC

  International Knee Documentation Committee (IKDC) Evaluation Form

  From surgery to 6 months

• MRI

  Knee Magnetic Resonance Imaging (MRI)

  6 months post surgery

Other Outcomes (1)

• Xray

  before surgery

Study Arms (2)

Isolated meniscus repair with microfracture

EXPERIMENTAL

isolated meniscus tear repair with notch microfracture

Procedure: Isolated meniscus repair with notch Microfracture

Isolated meniscus repair without microfracture

ACTIVE COMPARATOR

Typical meniscus repair without microfracture

Procedure: Isolated meniscus repair without notch microfracture

Interventions

Isolated meniscus repair with notch Microfracture PROCEDURE

prospective comparative study on isolated meniscus repair with and without microfracture

Isolated meniscus repair with microfracture

Isolated meniscus repair without notch microfracture PROCEDURE

Isolated meniscus repair without notch microfracture

Also known as: meniscus repair

Isolated meniscus repair without microfracture

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Isolated Lateral or Medial repairable meniscus tears
• Vertical Longitudinal meniscal tears.
• Adults aged 18-50 years-old
• Both Genders

You may not qualify if:

• Associated ligament injury.
• Associated bone angular deformity.
• Associated chondral injuries that require cartilage reconstruction procedures (microfracture, osteochondral graft or autologous chondrocyte implantation).
• Meniscal tears that occurred more than 6 months before the procedure.

Sponsors & Collaborators

• Ain Shams University: lead

Study Sites (1)

Ain Shams University Hospital

Cairo, Egypt

Location

MeSH Terms

Conditions

Fractures, Stress

Condition Hierarchy (Ancestors)

Fractures, Bone; Wounds and Injuries

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 20, 2026
• First Posted: May 27, 2026
• Study Start: December 1, 2025
• Primary Completion (Estimated): August 15, 2026
• Study Completion (Estimated): August 15, 2026
• Last Updated: May 27, 2026

Record last verified: 2025-09

Locations

EG (1)