Knee Arthroscopy Cohort Southern Denmark (KACS)
KACS
3 other identifiers
observational
491
1 country
4
Brief Summary
PURPOSE: To investigate the natural time course of patient-reported outcomes after meniscus surgery and identify factors associated with good and bad outcome after surgery.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Feb 2013
Typical duration for all trials
4 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 1, 2013
CompletedFirst Submitted
Initial submission to the registry
June 3, 2013
CompletedFirst Posted
Study publicly available on registry
June 6, 2013
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2015
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2015
CompletedJune 30, 2015
June 1, 2015
2.3 years
June 3, 2013
June 29, 2015
Conditions
Outcome Measures
Primary Outcomes (1)
Knee Injury and Osteoarthritis Outcome Score (KOOS)
Knee specific questionnaire. All domains on the KOOS. Primary end point is change from PRE surgery (assessed 1-14 days prior to surgery) to 52 weeks follow-up.
PRE surgery (assessed 1-14 days prior to surgery) and at 12 weeks and 52 weeks follow-up
Secondary Outcomes (3)
Medical Outcomes Study 36-Item Short Form Health Survey (SF-36)
PRE surgery (assessed 1-14 days prior to surgery) and at 12 weeks and 52 weeks follow-up.
Patient Acceptable Symptom State (PASS)
At 12 weeks and 52 weeks follow-up.
Treatment failure (TF)
At 12 weeks and 52 weeks follow-up.
Other Outcomes (1)
Global perceived effect (GPE)
At 12 weeks and 52 weeks follow-up.
Study Arms (1)
Meniscus Injury Patients
Patients having surgery for a meniscal tear.
Interventions
Surgery to the meniscus - resection or repair.
Eligibility Criteria
Patients assigned for arthroscopy on suspicion of a meniscus tear in the period from February 1st 2013 to January 31st 2014 will be consecutively recruited to the KACS cohort from 4 different hospitals (Lillebaelt Hospital - Kolding and Vejle and Odense University Hospital - Odense and Svendborg) in the Region of Southern Denmark.
You may qualify if:
- Assigned for arthroscopy on suspicion of a medial and/or lateral meniscus tear.
- Age \>18 years at time of recruitment
- Having an email address
- Able to read and understand Danish
You may not qualify if:
- Patients who will or have previously undergone surgical reconstruction of the anterior or posterior cruciate ligament (ACL or PCL) in either knee
- Fracture to the lower extremities (i.e. hip, leg or foot) in either leg within the last 6 months prior to recruitment
- Not mentally able to reply to the questionnaire
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Southern Denmarklead
- Odense University Hospitalcollaborator
- Lillebaelt Hospital, Kolding and Vejle, Denmarkcollaborator
Study Sites (4)
Department of Orthopedics, Lillebaelt Hospital
Kolding, Southern Denmark, 6000, Denmark
Department of Orthopedics and Traumatology, Odense University Hospital
Odense, Southern Denmark, 5000, Denmark
Department of Orthopedics and Traumatology, Odense University Hospital
Svendborg, Southern Denmark, 5700, Denmark
Department of Orthopedics, Lillebaelt Hospital
Vejle, Southern Denmark, 7100, Denmark
Related Publications (5)
Thorlund JB, Christensen R, Nissen N, Jorgensen U, Schjerning J, Porneki JC, Englund M, Lohmander LS. Knee Arthroscopy Cohort Southern Denmark (KACS): protocol for a prospective cohort study. BMJ Open. 2013 Oct 14;3(10):e003399. doi: 10.1136/bmjopen-2013-003399.
PMID: 24127057BACKGROUNDGiladi JO, Holsgaard-Larsen A, Varnum C, Thorlund JB. Sports Participation and Performance 5 Years After Arthroscopic Partial Meniscectomy: A Retrospective Cohort Study of 288 Patients. J Orthop Sports Phys Ther. 2022 Apr;52(4):224-232. doi: 10.2519/jospt.2022.10785.
PMID: 35442751DERIVEDPihl K, Ensor J, Peat G, Englund M, Lohmander S, Jorgensen U, Nissen N, Fristed JV, Thorlund JB. Wild goose chase - no predictable patient subgroups benefit from meniscal surgery: patient-reported outcomes of 641 patients 1 year after surgery. Br J Sports Med. 2020 Jan;54(1):13-22. doi: 10.1136/bjsports-2018-100321. Epub 2019 Jun 11.
PMID: 31186258DERIVEDThorlund JB, Pihl K, Nissen N, Jorgensen U, Fristed JV, Lohmander LS, Englund M. Conundrum of mechanical knee symptoms: signifying feature of a meniscal tear? Br J Sports Med. 2019 Mar;53(5):299-303. doi: 10.1136/bjsports-2018-099431. Epub 2018 Aug 31.
PMID: 30170997DERIVEDThorlund JB, Englund M, Christensen R, Nissen N, Pihl K, Jorgensen U, Schjerning J, Lohmander LS. Patient reported outcomes in patients undergoing arthroscopic partial meniscectomy for traumatic or degenerative meniscal tears: comparative prospective cohort study. BMJ. 2017 Feb 2;356:j356. doi: 10.1136/bmj.j356.
PMID: 28153861DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Jonas B Thorlund, PhD
Department of Sports Science and Clinical Biomechanics, University of Southern Denmark
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor
Study Record Dates
First Submitted
June 3, 2013
First Posted
June 6, 2013
Study Start
February 1, 2013
Primary Completion
June 1, 2015
Study Completion
June 1, 2015
Last Updated
June 30, 2015
Record last verified: 2015-06