Project to Improve the Diagnosis and Treatment Ability of Adult Severe Community Acquired Lower Respiratory Tract Infection

NCT04959955 | Completed DMC

• 1 other identifier: LM2016057
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

1. 1.Objective to understand the proportion of atypical pathogens in the pathogens of SCAP and AECOPD in urban hospitals in China.
2. 2.Objective to investigate the antimicrobial resistance of atypical pathogens in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) and SCAP in urban hospitals.
3. 3.Objective to master the important clinical characteristics of patients with acute exacerbation of SCAP and COPD caused by atypical pathogens and mixed infection in urban hospitals in China, and to put forward the experience judgment index.
4. 4.Objective to evaluate the advantages of various diagnostic methods for atypical pathogens causing lower respiratory tract infection.
5. 5.It is suggested that the current empirical treatment of SCAP and severe COPD in China should be improved.

Conditions

CAP; COPD Exacerbation

Outcome Measures

Primary Outcomes (1)

• Incidence of atypical pathogens and mixed infections

  Incidence of atypical pathogens and mixed infections

  2year Incidence

Study Arms (2)

AECOPD group

CAP group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Adult hospitalized cases of SCAP and acute exacerbation of COPD were collected from 12 medical institutions in 10 cities in China within 2 years.

You may qualify if:

• SCAP
• AECOPD

You may not qualify if:

• Pregnant or lactating women.
• Patients with bronchiectasis.
• Patients with active pulmonary tuberculosis.
• Aspiration pneumonia or obstructive pneumonia.
• Two weeks before the onset of hospital treatment history, this infection can not be excluded from hospital acquired infection.
• HIV positive patients (but HIV testing is not required).
• Patients who are unable and / or unable to understand and / or implement the investigation protocol.

Sponsors & Collaborators

• Peking University Third Hospital: lead
• First Hospital of China Medical University: collaborator

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 4, 2021
• First Posted: July 13, 2021
• Study Start: August 8, 2015
• Primary Completion: July 10, 2016
• Study Completion: December 12, 2019
• Last Updated: July 13, 2021

Record last verified: 2021-07

Data Sharing

• IPD Sharing: Will not share