NCT04958447

Brief Summary

The important role of nutritional management in the treatment of ICU patients has been paid more and more attention. Reasonable nutritional management can improve the nutritional status of patients, reduce the risk of malnutrition, shorten the length of ICU stay, improve the quality of life of patients, and reduce the mortality of patients, thereby improving the prognosis. Many studies have investigated the nutritional status and implementation of ICU patients. It is generally believed that the nutritional status of ICU patients is not good, and the implementation of standardization needs to be improved.The data on the nutritional status and implementation of RICU patients in mainland China is rare. Therefore, the main purpose of this study is to investigate the implementation and compliance of nutritional support treatment for RICU patients in mainland China.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

March 28, 2021

Completed
3 months until next milestone

Study Start

First participant enrolled

July 1, 2021

Completed
Same day until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2021

Completed
11 days until next milestone

First Posted

Study publicly available on registry

July 12, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

August 12, 2021

Completed
Last Updated

July 12, 2021

Status Verified

July 1, 2021

Enrollment Period

Same day

First QC Date

March 28, 2021

Last Update Submit

July 1, 2021

Conditions

Nutritional Deficiency

Keywords

Nutritional ManagementRespiratory Critically Ill PatientsEnteral Nutrition

Outcome Measures

Primary Outcomes (1)

  • Proportion of enteral nutrition starting within 48 hours after ICU entry

    Proportion of enteral nutrition starting within 48 hours after ICU entry

    48 hours

Secondary Outcomes (3)

  • Nutritional status and risk of malnutrition on ICU admission

    48 hours

  • The proportion of subjects receiving>80% estimated energy target within 7 days after ICU entry

    7 days

  • The proportion of enteral nutrition intolerance

    48 hours

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

The patients admitted to RICU

You may qualify if:

  • patients aged \>18 years
  • the length of RICU stays \>48 hours

You may not qualify if:

  • patients aged ≤18 years
  • the length of RICU stays ≤48 hours
  • patients who were admitted to RICU due to or combined with severe trauma or surgery

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

China-Japan Friendship hospital

Beijing, Beijing Municipality, 100028, China

RECRUITING

Related Publications (1)

  • Huang X, Wang Y, Geng S, Liang Y, Gao F, Wang T, Zhang H, Fang J, Wang C, Gu X, Yang J, Cheng Z, Liu C, Lei W, Hu X, Luo H, Fan H, Zhang Y, Li G, Di Q, Xing L, Li Y, Tong J, Chen L, Sun W, Chen L, Wang S, Li S, Liu J, Qin H, Qiu X, Ma Z, Li Y, Zhao H, Liang R, Wang L, Gao P, Sang L, Li D, Hou P, Zhang X, Wang D, Zheng L, Hua F, Jiang J, Li X, Nie Q, Zhao H, Huang C, Ji Y, Yu H, Song L, Jin J, Li N, Qian W, Zeng J, Chen L, Sun J, He W, Guan S, Chai S, Hu S, Li G, Li J, Jiang H, Zhong X, Li J, Zhao J, Du W, Zhang J, Liu Z, van Zanten A, Tian Y, Cai Y, Zhan Q. Nutritional practices and impact of feeding adequacy on clinical outcomes in Chinese respiratory intensive care units patients: a prospective observational study (ORIENT study). Front Nutr. 2026 Jan 20;12:1719386. doi: 10.3389/fnut.2025.1719386. eCollection 2025.

    PMID: 41640734DERIVED

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic Diseases

Central Study Contacts

Xu Huang, M.D.

CONTACT

13641345816huangxu1122@sina.com

Qingyuan Zhan, M.D.

CONTACT

13911785957drzhanqy@163.com

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

March 28, 2021

First Posted

July 12, 2021

Study Start

July 1, 2021

Primary Completion

July 1, 2021

Study Completion

August 12, 2021

Last Updated

July 12, 2021

Record last verified: 2021-07

Data Sharing

IPD Sharing
Will not share

Locations

CN(1)