High Intensity Interval Training Versus Intermittent Fasting on Functional Capacity Among Overweight Subjects

NCT04950062 | Completed

• 1 other identifier: Manar_MSc
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of the study is to compare the effect of high-intensity interval training and intermittent fasting on improving body weight and functional capacity among overweight subjects.

Conditions

Overweight

Outcome Measures

Primary Outcomes (3)

• Assessing the change in Vo2max

  Assessment via using Standard Bruce protocol will be used to measure (VO2) max. The Bruce protocol for multi stage treadmill testing of maximal exercise will be used. This will begin with stage 1 with walking slowly for three minutes at 2.7 Km/hr at a 10% grade (inclination), speed and grade then increased in every stage of 3 minutes and end at stage 7 or till exhaustion.

  Baseline and 2 months post-intervention

• Assessing the change in body weight

  Assessment via using of body weight scale with height (m) scale to be able to calculate body weight (Kg).

  Baseline and 2 months post-intervention

• Assessing the change in waist hip circumference

  Assessment via using Tape measures It will be used to measure waist and hip circumference and calculate waist hip ratio

  Baseline and 2 months post-intervention

Study Arms (2)

High intensity interval training

EXPERIMENTAL

Group A included 30 subjects who will participate in high intensity interval training on a treadmill for 12 weeks, 3 times/week.

Other: High Intensity Interval Training

Intermittent fasting

ACTIVE COMPARATOR

Group B that included 30 subjects will participate in intermittent fasting for 12 weeks, 3 times/week.

Other: Intermittent Fasting 16/8 Protocol

Interventions

High Intensity Interval Training OTHER

1. Warming up period for 5 min at an intensity corresponding to 65-75% of heart rate maximum (HRmax). 2. Training phase for 30 min divided into four sets of 4-min length each at intensity equals 80-90% of HRmax interspersed by 3 minutes low intensity walking at the level of 65-75% of HRmax. 3. Cooling down period for 5 min of at 50-60% of the HRmax. All subjects will be trained at the lower intensity limit for the first 2 weeks of the program before increasing the intensity levels toward the upper limit.

High intensity interval training

Intermittent Fasting 16/8 Protocol OTHER

Every subject will be instructed to fast a fixed 16 hours followed by 8 hours of eating every day through the whole study period based on their life and sleeping style. During fasting, zero-calorie coffee, tea and water intake will be permitted. Beverages containing calories were consumed during the feeding hours each day. All subjects will be instructed about their optimum caloric requirement based on their basal metabolic rate that will be calculated in advance to avoid over consumption of food on severe caloric restriction as we like to investigate the effect of this way of fasting on reducing weight and improving functional capacity.

Intermittent fasting

Eligibility Criteria

• Age: 25 Years - 35 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Subjects have to meet all the following criteria in order to participate in the study:
• Overweight subjects with age from 25 to 35 years.
• Body mass index will be range from 25 to 29.9 kg/m2.
• Waist circumference ≥ 80 cm2.
• A minimum of 70% of exercise program and diet regimen compliance will be required in order to be included.

You may not qualify if:

• Subjects with the following disorders will be excluded from participating in this study:
• Musculoskeletal, cardiovascular disorders.
• Asthma, chronic obstructive pulmonary diseases.
• Any systemic disease or condition that might reduce adherence or tolerance to exercise or fasting.
• History of stroke.

Sponsors & Collaborators

• Horus University: lead

Study Sites (1)

Outpatient clinic - Faculty of Physical Therapy - Horus University

Damietta, 34518, Egypt

Location

MeSH Terms

Conditions

Overweight

Interventions

High-Intensity Interval Training

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Physical Conditioning, Human; Exercise; Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Manar Elbaz, Demonstrator

  Horus University in Egypt

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: June 12, 2021
• First Posted: July 6, 2021
• Study Start: February 1, 2021
• Primary Completion: June 15, 2021
• Study Completion: June 30, 2021
• Last Updated: July 6, 2021

Record last verified: 2021-06

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)