BFR in Overweight Sedentary Subjects

NCT05371119 | Completed DMC

• 1 other identifier: 2021-02081
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This project should allow the investigators to observe the effects of low load training under partial vascular occlusion (BFR) in comparison with resistance training at low load without partial vascular occlusion in sedentary people overweight on parameters : decrease in fat mass; increase in muscle mass 79; muscle strength; decrease in the energy cost of walking; increase in preferred walking speed; improvement in walking pattern in patients overweight. Training under partial vascular occlusion should facilitate physical activity in overweight people as it can be just as effective as a "classic" type training with heavy loads. Thus, this device could allow people for who wear heavy loads can present an obstacle to physical activity to feel more involved in the physical activity programs offered in medical or sports centers.

Conditions

Overweight

Keywords

blood flow restriction

Outcome Measures

Primary Outcomes (10)

• DEXA technology

  Body composition assessment: relative lean and fat mass in all body segments

  One week before intervention

• DEXA technology

  Body composition assessment: relative lean and fat mass in all body segments

  One week following the training intervention

• Evaluation of muscle strength from an isokinetic device

  eccentric and concentric peak torque of the knee extensor muscles

  One week before intervention

• Evaluation of muscle strength from an isokinetic device

  eccentric and concentric peak torque of the knee extensor muscles

  One week following the training intervention

• Evaluation of the preferential speed of walking in an ecological situation

  using of a treadmill with measurement of the ground reaction forces

  One week before interventionn

• Evaluation of the preferential speed of walking in an ecological situation

  using of a treadmill with measurement of the ground reaction forces

  One week following the training intervention

• Analysis of the biomechanics of walking on a treadmill instrumented with power platforms.

  calculation of the mechanical work

  One week before intervention

• Analysis of the biomechanics of walking on a treadmill instrumented with power platforms.

  calculation of the mechanical work

  One week following the training intervention

• Evaluation of the energy cost of walking

  on a treadmill, by indirect calorimetry with gaz exchanges

  One week before intervention

• Evaluation of the energy cost of walking

  on a treadmill, by indirect calorimetry with gaz exchanges

  One week following the training intervention

Study Arms (2)

Blood Flow Restriction

EXPERIMENTAL

Use of the BFR cuff during the training intervention

Other: Exercise Intervention

control

ACTIVE COMPARATOR

No use of inflated cuff

Other: Exercise Intervention

Interventions

Exercise Intervention OTHER

Training with light load with blood flow restriction (BFR)

Blood Flow Restriction; control

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• IMC between 25 and 35
• vaccin against Covid-19

You may not qualify if:

• hypertension diabete

Sponsors & Collaborators

• University of Lausanne: lead

Study Sites (1)

ISSUL

Lausanne, Canton of Vaud, 1015, Switzerland

Location

MeSH Terms

Conditions

Overweight

Condition Hierarchy (Ancestors)

Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: PARTICIPANT
• Masking Details: BFR inflated 20 mmHg
• Purpose: BASIC SCIENCE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Model Details: The procedure will consist of 6 weeks of training with or without partial vascular occlusion (depending on group A or group B) at the rate of 3 sessions per week (for a total of 18 training sessions).

Study Record Dates

• First Submitted: April 19, 2022
• First Posted: May 12, 2022
• Study Start: February 1, 2022
• Primary Completion: April 15, 2022
• Study Completion: April 15, 2022
• Last Updated: May 12, 2022

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)