NCT04943510

Brief Summary

This is a monocentric study comparing hamstring and quadriceps neuromuscular fatigue after simulated soccer game, anaerobic and aerobic training sessions. The purpose of this study was:

  1. 1.To quantify the decrease of isometric force immediately after a simulate soccer game.
  2. 2.To characterize peripheral and central fatigue between hamstring and quadriceps muscles and described the kinetics of recovery after specific tasks of soccer training.
  3. 3.To compare the level neuromuscular fatigue induced by anaerobic and aerobic training.
  4. 4.To highlight correlation between neuromuscular fatigue and performance markers.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15

participants targeted

Target at below P25 for phase_2

Timeline
Completed

Started Nov 2021

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 2, 2021

Completed
27 days until next milestone

First Posted

Study publicly available on registry

June 29, 2021

Completed
4 months until next milestone

Study Start

First participant enrolled

November 4, 2021

Completed
1.7 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2023

Completed
Last Updated

April 27, 2022

Status Verified

April 1, 2022

Enrollment Period

1.7 years

First QC Date

June 2, 2021

Last Update Submit

April 19, 2022

Conditions

Keywords

HamstringNeuromuscular fatigueSoccerPerformance

Outcome Measures

Primary Outcomes (1)

  • Difference in maximal isometric hamstring strength before and immediately after exercise (i.e., pre vs. immediate post exercise) expressed as a percentage (%).

    Before and immediately post exercise (i.e., during the first minute after cessation of exercise)

Secondary Outcomes (11)

  • Relative difference (in %) in maximum isometric hamstring strength before and after exercise (i.e., pre- vs. post-exercise), relative to pre-exercise strength across different test types.

    Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise

  • Relative difference (in %) in maximal isometric quadriceps strength before and after exercise (i.e., pre vs. post exercise), related to preexercise strength according to the different types of tests.

    Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise

  • Relative difference (%) in maximum isometric hamstring and quadriceps strength for each test type at the different times of interest.

    Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise

  • Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) hamstring potentiated jerk amplitude (N) relative to pre-exercise amplitude by event type at different times of interest.

    Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise

  • Difference in pre- and post-exercise (i.e., pre- vs. post-exercise) potentiated jerk amplitude (N) of the quadriceps, relative to pre-exercise amplitude, by test type at different times of interest.

    Before and immediately post exercise, 5, 10, 15, 30-minutes and 24 and 48-hours post-exercise

  • +6 more secondary outcomes

Study Arms (1)

Physical exercices arm

EXPERIMENTAL

three randomizations will be used to determine the order of the tests that will be proposed to the subjects: on the one hand for the exercise modalities (match, anaerobic, aerobic) and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linear

Other: Physical exercices

Interventions

surface EMG: surface electrodes will be positioned on the muscles to evaluate the level of muscle activation non invasive muscular neurostimulations : application of a percutaneous electrical stimulation of the motor nerve of the considered muscle and a direct electrical stimulation of the muscle

Also known as: Non invasive muscular neurostimulations, Surface EMG
Physical exercices arm

Eligibility Criteria

Age16 Years - 40 Years
Sexmale
Healthy VolunteersYes
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • male
  • age limits: minimum: 16 ; maximum: 40 years old
  • to be a soccer player, licensed to the French Football Federation
  • affiliation to the social health insurance scheme
  • signing an informed consent form

You may not qualify if:

  • impossibility to give the subject enlightened information (subject in emergency situation, difficulties in understanding the study, …)
  • subject under the protection of justice
  • subject under guardianship or curatorship
  • lower limbs musculotendinous or articular problems
  • smoker or having been a smoker in the last 5 years
  • subject wearing a pacemaker
  • drug treatment in progress and impossibility to stop it within 7 days before the beginning of the study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Hopitaux Universitaires de Strasbourg

Strasbourg, 67091, France

RECRUITING

MeSH Terms

Conditions

Motor Activity

Condition Hierarchy (Ancestors)

Behavior

Study Design

Study Type
interventional
Phase
phase 2
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Model Details: three randomizations will be used to determine the order of the tests that will be proposed to the subjects: * on the one hand for the exercise modalities (match, anaerobic, aerobic) * and, on the other hand, for the exercise modalities included in the anaerobic and aerobic exercise families: Anaerobic agility / anaerobic - linear sprints Aerobic - shuttle / aerobic - linear
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 2, 2021

First Posted

June 29, 2021

Study Start

November 4, 2021

Primary Completion

July 1, 2023

Study Completion

July 1, 2023

Last Updated

April 27, 2022

Record last verified: 2022-04

Locations