Exploring Hand Function in People With Schizophrenia Based on Perspective of Sensorimotor Control

NCT04941677 | Completed

• 1 other identifier: B-ER-109-188
• Study Type: observational
• Target: 37
• Locations: 1 country
• Sites: 1

Brief Summary

The study aims to explore the hand function in people with schizophrenia in the chronic stage.

Conditions

Schizophrenia

Keywords

hand function; sensorimotor; motor control theory

Outcome Measures

Primary Outcomes (5)

• Semmes Weinstein Monofilaments

  Semmes Weinstein Monofilaments is used to assess cutaneous pressure thresholds.

  baseline

• Pinch-holding-up-activity test

  The pinch apparatus is aims to assess the ability to modulate pinch force to movement-induced load fluctuations in a pinch-holding-up activity (PHUA).

  baseline

• Manual Tactile Test

  Manual tactile test (MTT) aims to assess the capacity of barognosis, roughness differentiation and stereognosis.

  baseline

• Purdue pegboard test

  The purpose for Purdue pegboard test is to measure manipulative dexterity including unimanual and bimanual hand dexterity.

  baseline

• The Valpar 8 simulates assembly work assessment

  Valpar8 simulates the light work and assess the ability of manual dexterity and motor coordination.

  baseline

Secondary Outcomes (1)

• Self-reported version of the graphic Personal and Social Performance (SRG-PSP)

  baseline

Study Arms (1)

schizophrenia group

No intervention age between 20-65, diagnosed schizophrenia by DSM-5.

Other: no intervention

Interventions

no intervention OTHER

no intervention in this study

schizophrenia group

Eligibility Criteria

• Age: 20 Years - 65 Years
• Sex: all
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants with schizophrenia will be recruited from the Department of Internal Medicine in National Cheng Kung University Hospital

You may qualify if:

• Age between 20-65 years old
• Diagnosis with schizophrenia or schizoaffective disorder by psychiatrists according to DSM5.
• Remaining the same antipsychotics and the symptom was stable for at least one month before the study.
• Be able to follow comments and have sufficient cognitive ability assessed by Mini-Mental State Examination score \>24

You may not qualify if:

• Substance abuse or other medical conditions that may affect movements.
• Using other non-antipsychotics that will affect movements in the same period.

Sponsors & Collaborators

• National Cheng-Kung University Hospital: lead

Study Sites (1)

National Cheng-Kung University

Tainan, 701, Taiwan

Location

Related Publications (1)

• Lai YJ, Lin YC, Hsu CH, Tseng HH, Lee CN, Huang PC, Hsu HY, Kuo LC. Are the sensorimotor control capabilities of the hands the factors influencing hand function in people with schizophrenia? BMC Psychiatry. 2023 Nov 7;23(1):807. doi: 10.1186/s12888-023-05259-w.

  PMID: 37936136 DERIVED

MeSH Terms

Conditions

Schizophrenia

Condition Hierarchy (Ancestors)

Schizophrenia Spectrum and Other Psychotic Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Month
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 20, 2021
• First Posted: June 28, 2021
• Study Start: September 17, 2020
• Primary Completion: July 31, 2022
• Study Completion: December 31, 2022
• Last Updated: April 3, 2024

Record last verified: 2024-04

Locations

TW (1)