Investigation of Hand Functions and Related Parameters in People With Multiple Sclerosis

NCT04933110 | Unknown

• 1 other identifier: İAÜ2
• Study Type: observational
• Target: 90
• Locations: 0 countries
• Sites: N/A

Brief Summary

The upper extremity in people with Multiple Sclerosis (pwMS) has become a more popular research topic in recent years, with the increase in studies reporting widespread involvement. The aim of our study was to evaluate the upper extremity from multiple perspectives in early stage pwMS, to identify problems by comparing them with healthy individuals, and to examine the relationship of problems with activity and participation.

Conditions

Multiple Sclerosis

Keywords

multiple sclerosis; upper limb function; activity; participation

Outcome Measures

Primary Outcomes (5)

• Nine Hole Peg Test

  To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function.

  baseline (on the predetermined assessment day)

• Minnesota Manual Dexterity Test

  To assess upper extremity function. Completing the test in a short time (seconds) indicates better upper extremity function.

  baseline (on the predetermined assessment day)

• ABILHAND

  To assess for performance of activity. Score range 0-46 point, higher scores mean a better outcome.

  baseline (on the predetermined assessment day)

• Motor Activity Log-28

  To assess for performance of activity. Score range 0-5 point, a high score indicates good upper extremity use frequency and quality of movement during activity.

  baseline (on the predetermined assessment day)

• Community Integration Questionnaire

  To assess participation. The total score ranges from 0-29, and the higher the score, the higher the individual's participation in society is considered.

  baseline (on the predetermined assessment day)

Secondary Outcomes (8)

• Hand Held Dynamometer

  baseline (on the predetermined assessment day)

• Hand Dynamometer

  baseline (on the predetermined assessment day)

• Pinchmeter

  baseline (on the predetermined assessment day)

• Tuning fork

  baseline (on the predetermined assessment day)

• Aesthesiometer

  baseline (on the predetermined assessment day)

Study Arms (2)

Multiple Sclerosis

Individuals with early-stage multiple sclerosis

Healthy Volunteers

Healthy volunteers of similar age and sex as individuals with multiple sclerosis

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Individuals with MS who met the inclusion criteria and volunteered to participate in the study. Volunteer healthy individuals of similar age and sex with individuals with MS.

You may qualify if:

• MS diagnosis according to McDonald criteria
• Relapsing Remitting MS clinical course type
• age range
• Being able to understand and read Turkish

You may not qualify if:

• Having an MS attack in the last 3 months
• To have done regular exercise for the upper extremity in the 6 months before starting the study
• Having different neurological, orthopedic or cardiac problems other than MS
• Being addicted to alcohol or drugs
• Getting a score below 24 on the Mini Mental Test Scale
• Having a spasticity of 3 or more according to the Modified Ashworth Scale

Sponsors & Collaborators

• Uğur OVACIK: lead
• Istanbul University - Cerrahpasa: collaborator

MeSH Terms

Conditions

Multiple Sclerosis; Motor Activity

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases; Behavior

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Principal Investigator, PT, Msc

Study Record Dates

• First Submitted: June 14, 2021
• First Posted: June 21, 2021
• Study Start: July 5, 2021
• Primary Completion: September 6, 2021
• Study Completion: September 20, 2021
• Last Updated: June 25, 2021

Record last verified: 2021-06