NCT04919941

Brief Summary

This is a randomized pilot study to test the feasibility and acceptability of a patient decision aid on conservative care among older patients with advanced CKD and their close persons.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
92

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Aug 2020

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 31, 2020

Completed
9 months until next milestone

First Submitted

Initial submission to the registry

May 28, 2021

Completed
12 days until next milestone

First Posted

Study publicly available on registry

June 9, 2021

Completed
8 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2022

Completed
Last Updated

June 24, 2022

Status Verified

June 1, 2021

Enrollment Period

1.4 years

First QC Date

May 28, 2021

Last Update Submit

June 18, 2022

Conditions

Keywords

conservative care

Outcome Measures

Primary Outcomes (2)

  • Questionnaire on patient-provider discussions of conservative care .

    Using a questionnaire, patients will be asked whether they had discussed conservative care with any of their healthcare providers prior to T1 and by T3. Possible responses are "yes", "no" or "unsure." Greater motivation to discuss conservative care with their care providers at T3 after would indicate that the Guide is acceptable to patients and can be feasibly incorporated by them into their care planning.

    3 months

  • Attrition

    The proportion of participants in each study arm who withdraw from the study and the reasons why at T2 and T3. Study withdrawal would indicate that the Guide and/or study is unacceptable or burdensome to the participant.

    3 months

Secondary Outcomes (4)

  • Treatment Preference

    3 months

  • Treatment Goals

    3 months

  • Guide Questionnaire

    2 weeks

  • Guide Interview

    3 months

Study Arms (2)

Decision aid

EXPERIMENTAL

The intervention is receipt of a patient decision aid on conservative care, entitled A Guide to Conservative Care. This is 12-page printed handout that provides an overview of conservative care. Participants assigned to the intervention group are mailed a copy of the Guide after their initial baseline visit (T1). Participants keep the Guide throughout the duration of the study.

Other: A Guide to Conservative Care

Control

NO INTERVENTION

Did not receive the decision aid.

Interventions

The intervention is receipt of a patient decision aid on conservative care, entitled A Guide to Conservative Care. This is 12-page printed handout that provides an overview of conservative care. Participants assigned to the intervention group are mailed a copy of the Guide after their initial baseline visit (T1). Participants keep the Guide throughout the duration of the study.

Decision aid

Eligibility Criteria

Age75 Years+
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Patients
  • Adults aged ≥75 years
  • Diagnosis of advanced CKD as defined as having at least 2 outpatient measures of eGFR \<25 ml/min/1.73m2 separated by \>90 days in the prior year and with at least 1 of these measures of eGFR \<20 ml/min/1.73m2
  • Must be english-speaking
  • Close persons
  • Adults aged ≥18 years
  • Must assist patient with their kidney disease care
  • Must be English-speaking

You may not qualify if:

  • Patients and Close Person
  • Unable to provide informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

VA Puget Sound Health Care System

Seattle, Washington, 98108, United States

Location

University of Washington Medicine

Seattle, Washington, 98198, United States

Location

Related Publications (1)

  • Wong SPY, Oestreich T, Prince DK, Curtis JR. A Patient Decision Aid About Conservative Kidney Management in Advanced Kidney Disease: A Randomized Pilot Trial. Am J Kidney Dis. 2023 Aug;82(2):179-188. doi: 10.1053/j.ajkd.2022.12.007. Epub 2023 Feb 4.

MeSH Terms

Conditions

Kidney Failure, ChronicPatient Participation

Condition Hierarchy (Ancestors)

Renal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsPatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehavior

Study Officials

  • Susan P Wong, MD

    University of Washington

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
INVESTIGATOR, OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Model Details: Test feasibility and acceptability of a patient decision aid
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor, School of Medicine: Nephrology

Study Record Dates

First Submitted

May 28, 2021

First Posted

June 9, 2021

Study Start

August 31, 2020

Primary Completion

January 31, 2022

Study Completion

April 30, 2022

Last Updated

June 24, 2022

Record last verified: 2021-06

Data Sharing

IPD Sharing
Will share

All de-identified individual participant data collected and study protocols will be shared immediately following publication and ending 5 years following article publication with researchers who provide a written request and sound research proposal. Interested researchers can contact the principal investigator directly.

Shared Documents
STUDY PROTOCOL
Time Frame
Immediately following publication and through 5 years after article publication
Access Criteria
Written request and sound research plan.

Locations