Motor Imagery Training in Persons With Multiple Sclerosis

NCT02781142 | Completed

• 1 other identifier: 2628-GOA
• Study Type: interventional
• Target: 70
• Locations: 1 country
• Sites: 2

Brief Summary

Motor imagery training facilitates the neural plasticity with increasing the neuronal cortical pathways in the brain. Motor imagery training is an effective way in stroke survivors. However, its effects in persons with multiple sclerosis (MS) are not known. Additionally, telerehabilitation based motor imagery training is very rare treatment way which requires more research. Therefore, this study aims to investigate the effect of telerehabilitation based motor imagery training on gait and balance performance of the persons with MS. The participants will be allocated into three groups, including motor imagery training, wait-list control group, and healthy control group. All the assessments will be performed before and after the training in the 8-week motor imagery training group. The participants in the control group will underwent the assessment with a 8-week interval. The healthy participants will be assessed only one. The motor imagery training will be designed for the individual basis with following standard protocols. It will be applied two times a week for 8 weeks. The first one and/or two sessions will be performed in the clinic, the other will be performed at the patients' home with a video-conference telerehabilitation technique.

Conditions

Multiple Sclerosis

Outcome Measures

Primary Outcomes (1)

• Dynamic Gait Index

  Change from Baseline at 8 weeks

Secondary Outcomes (28)

• Expanded Disability Status Scale

  At Baseline

• Kinesthetic and Visual Imagery Questionnaire (KVIQ)-10

  Change from Baseline at 8 weeks

• Movement Imagery Questionnaire-Revised Second Edition (MIQ-RS)

  Change from Baseline at 8 weeks

• Mental Chronometry for 2-Meter Walk Test

  Change from Baseline at 8 weeks

• Mental Chronometry for 5-Meter Walk Test

  Change from Baseline at 8 weeks

Study Arms (3)

Motor imagery training

EXPERIMENTAL

Persons with multiple sclerosis

Other: Motor imagery training

Control group

NO INTERVENTION

Persons with multiple sclerosis

Healthy controls

NO INTERVENTION

Healthy participants

Interventions

Motor imagery training OTHER

The motor imagery training will be designed for the individual basis with following standard protocols. It will be applied two times a week for 8 weeks. The first one and/or two sessions will be performed in the clinic, the other will be performed at the patients' home with a video-conference telerehabilitation technique.

Motor imagery training

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Diagnosis of multiple sclerosis
• Having the Expanded Disability Status Scale 0 - 4.0
• Relapse-free period at the last 3 months
• Enough computer use ability
• Having computer and internet connection

You may not qualify if:

• Having severe musculoskeletal, cardiovascular, pulmonary, or metabolic disease
• Severe cognitive impairment
• Pregnancy

Sponsors & Collaborators

• Dokuz Eylul University: lead

Study Sites (2)

Dokuz Eylul University Hospital, MS Outpatient Clinic

Izmir, 35430, Turkey (Türkiye)

Location

Dokuz Eylul University, School of Physical Therapy and Rehabilitation

Izmir, 35430, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Multiple Sclerosis

Condition Hierarchy (Ancestors)

Demyelinating Autoimmune Diseases, CNS; Autoimmune Diseases of the Nervous System; Nervous System Diseases; Demyelinating Diseases; Autoimmune Diseases; Immune System Diseases

Study Officials

• Sema Savci, Prof, PhD

  Dokuz Eylul University

  STUDY DIRECTOR

• Turhan Kahraman, MSc

  Dokuz Eylul University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: MSc

Study Record Dates

• First Submitted: May 17, 2016
• First Posted: May 24, 2016
• Study Start: May 1, 2016
• Primary Completion: October 1, 2017
• Study Completion: November 1, 2017
• Last Updated: April 3, 2018

Record last verified: 2018-03

Locations

TU (2)