NCT05669131

Brief Summary

The goal of this clinical trial is learn about motor imagery training (i.e. imagining a task) with healthy older adults. The main question this clinical trial aims to answer is:

  • Will imagining a task improve control of force during an elbow flexion muscle contraction in healthy older adults? Participants will:
  • Complete questionaries about general activity levels and ability to imagine tasks
  • Perform either motor imagery training or watch a documentary
  • Perform maximal and submaximal elbow flexion contractions Researchers will compare the motor imagery training with the control group to see if control of force is improved in the motor imagery training group.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P50-P75 for not_applicable healthy

Timeline
Completed

Started Dec 2022

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 29, 2022

Completed
2 days until next milestone

Study Start

First participant enrolled

December 1, 2022

Completed
29 days until next milestone

First Posted

Study publicly available on registry

December 30, 2022

Completed
7 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

August 1, 2023

Completed
Last Updated

December 30, 2022

Status Verified

December 1, 2022

Enrollment Period

8 months

First QC Date

November 29, 2022

Last Update Submit

December 29, 2022

Conditions

Keywords

AgedAged, 80 and over

Outcome Measures

Primary Outcomes (3)

  • Force steadiness

    Measured as the the coefficient in variation of force

    Within one session: Change from baseline (immediately before session) to 20 minutes after the session

  • Corticospinal excitability

    Measured as the peak-to-peak amplitude of a motor evoked potential

    Within one session: Change from baseline (immediately before session) to 20 minutes after the session

  • Common synaptic input

    Estimated from motor unit discharge times.

    Within one session: Change from baseline (immediately before session) to 20 minutes after the session

Secondary Outcomes (1)

  • Maximal elbow flexion force

    Within one session: Change from baseline (immediately before session) to 20 minutes after the session

Study Arms (2)

Motor Imagery Training

EXPERIMENTAL

Participants will do motor imagery training in 5 minute blocks for a total of 20 minutes.

Other: Motor imagery training

Control

NO INTERVENTION

Participants will watch a documentary in 5 minute blocks for a total of 20 minutes.

Interventions

Participants imagine themselves through their own eyes performing submaximal elbow flexion contractions.

Motor Imagery Training

Eligibility Criteria

Age65 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsOlder Adult (65+)

You may qualify if:

  • Healthy older adults aged 65 to 90 years old

You may not qualify if:

  • have had an injury or orthopaedic surgery to the arm or shoulder in the prior 6 months
  • are involved in high levels of upper-body strength training
  • have history of training in fine motor tasks (i.e., musicians)
  • have a history of MIT
  • have systemic diseases and/or nerve damage affecting neuromuscular function
  • have severe cognitive impairment
  • are unable to read or speak English fluently
  • are left hand dominant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Officials

  • Jennifer Jakobi, PhD

    University of British Columbia- Okanagan

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Jennifer Jakobi, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
PARALLEL
Model Details: Participants will be randomly assigned to either the motor imagery training group or the control group.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor

Study Record Dates

First Submitted

November 29, 2022

First Posted

December 30, 2022

Study Start

December 1, 2022

Primary Completion

August 1, 2023

Study Completion

August 1, 2023

Last Updated

December 30, 2022

Record last verified: 2022-12