NCT04911829

Brief Summary

The study evaluates cost and effect of inpatient versus outpatient treatment of dysthymia, as well as investigates the processes through which psychotherapy works in treating dysthymia.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
80

participants targeted

Target at P25-P50 for not_applicable depression

Timeline
7mo left

Started Jan 2016

Longer than P75 for not_applicable depression

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress95%
Jan 2016Dec 2026

Study Start

First participant enrolled

January 1, 2016

Completed
1.4 years until next milestone

First Submitted

Initial submission to the registry

May 15, 2017

Completed
4.1 years until next milestone

First Posted

Study publicly available on registry

June 3, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2026

Expected
Last Updated

June 3, 2021

Status Verified

May 1, 2021

Enrollment Period

5.9 years

First QC Date

May 15, 2017

Last Update Submit

May 31, 2021

Conditions

Keywords

DysthymiaPersistent depressive disorderChronic depressionRecurrent depression

Outcome Measures

Primary Outcomes (3)

  • Change in Depressive symptoms

    Beck depression inventory

    At assessment, start (12 weeks after assessment) and end (24 weeks after assessment) of therapy, and at one-year follow up (76 weeks after assessment).

  • Change in Depressive symptoms

    Patient health questionnaire

    Once every week for the 12 weeks of active psychotherapy

  • Change in Cost of living with dysthymia

    cost of living with dysthymia, cost-effectiveness of therapy at one-year and at 10 years. Information will be gathered from various registries and combined to a sum of money.

    pre therapy, one-year and 10 years

Secondary Outcomes (11)

  • Emotional psychological processes

    Once every week for the 12 weeks of active psychotherapy

  • cognitive psychological processes

    Once every week for the 12 weeks of active psychotherapy

  • metacognitive psychological processes

    Once every week for the 12 weeks of active psychotherapy

  • Common factors-alliance

    Once every week for the 12 weeks of active psychotherapy

  • Common factors-expectations

    Once every week for the 12 weeks of active psychotherapy

  • +6 more secondary outcomes

Study Arms (2)

Inpatient treatment

ACTIVE COMPARATOR

High intensity high dosage inpatient short-term psychodynamic psychotherapy

Behavioral: Psychotherapy

Outpatient treatment

EXPERIMENTAL

Low dosage outpatient short-term psychodynamic psychotherapy

Behavioral: Psychotherapy

Interventions

PsychotherapyBEHAVIORAL
Inpatient treatmentOutpatient treatment

Eligibility Criteria

Age18 Years - 70 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may not qualify if:

  • current suicidal risk, current psychosis, marked emotional instability (i.e. issues with impulsivity), strong paranoid traits, current problems related to heavy substance abuse.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Modum Bad

Vikersund, Buskerud, 3370, Norway

RECRUITING

MeSH Terms

Conditions

DepressionDysthymic Disorder

Interventions

Psychotherapy

Condition Hierarchy (Ancestors)

Behavioral SymptomsBehaviorDepressive DisorderMood DisordersMental Disorders

Intervention Hierarchy (Ancestors)

Behavioral Disciplines and Activities

Study Officials

  • Pål Ulvenes, PhD

    Modum Bad

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Pål Ulvenes, PhD

CONTACT

Linne Melsom, Cand.Psy

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 15, 2017

First Posted

June 3, 2021

Study Start

January 1, 2016

Primary Completion

December 1, 2021

Study Completion (Estimated)

December 1, 2026

Last Updated

June 3, 2021

Record last verified: 2021-05

Locations