Symptom Clusters in Hong Kong Chinese Children With Blood Cancer

NCT04888195 | Unknown

• 1 other identifier: SC_Blood_cancer
• Study Type: observational
• Target: 120
• Locations: 1 country
• Sites: 1

Brief Summary

Pediatric blood cancer is the most common childhood malignancy. Despite its survival has been substantially improved, children still have to pay a high price for numerous distressing symptoms resulted from chemotherapy. Previous studies related to symptom experiences mainly focus on individual symptoms, rather than on multiple symptoms. Understanding these distressing symptoms may help healthcare professionals to develop appropriate and effective interventions with the aims of alleviating symptom severity and thus promoting the child's psychosocial well-being and quality of life.

Conditions

Child

Keywords

blood cancer; chemotherapy

Outcome Measures

Primary Outcomes (6)

• The therapy-related symptom checklist for children (TRSC-C)

  For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.

  Before chemotherapy

• The therapy-related symptom checklist for children (TRSC-C) at 1-week

  For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.

  At 1-week follow-up

• The therapy-related symptom checklist for children (TRSC-C) at 1-month

  For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.

  At 1-month follow-up

• The therapy-related symptom checklist for children (TRSC-C) at 3-month

  For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.

  At 3-month follow-up

• The therapy-related symptom checklist for children (TRSC-C) at 6-month

  For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.

  At 6-month follow-up

• Demographic sheet

  collect the background information of our subjects, including their age, gender, educational attainment, parents' marital status and religious belief

  At baseline

Study Arms (1)

Questionnaire

This study aims to examine the cancer patient's symptom clusters and their changes over chemotherapy among pediatric patients with blood cancer in Hong Kong

Other: Questionnaire

Interventions

Questionnaire OTHER

Participants will complete a set of validated questionnaires (TRSC-C and demographic sheet) before chemotherapy. They also have to complete the same questionnaires (TRSC-C) again within 1 week after the 1st, 2nd, 3rd, 4th , 5th and 6th courses of chemotherapy via telephone interview by our research assistants.

Questionnaire

Eligibility Criteria

• Age: 5 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

We will recruit pediatric patients with blood cancer in the Hong Kong Children's Hospital

You may qualify if:

• aged 5 - 17 years old
• diagnosed with blood cancer but not yet receive any chemotherapy
• able to communicate with Cantonese and read Chinese

You may not qualify if:

• who are scheduled to have concurrent cancer treatment
• with recurrent malignancy
• medical condition, or cognitive and learning problems in their medical records

Sponsors & Collaborators

• The Hong Kong Polytechnic University: lead

Study Sites (1)

Ka Yan Ho

Hong Kong, Hong Kong,China, 0000, Hong Kong

RECRUITING

MeSH Terms

Conditions

Hematologic Neoplasms

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Hematologic Diseases; Hemic and Lymphatic Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Officials

• Ka Yan Ho, PhD

  The Hong Kong Polytechnic University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Ka Yan Ho, PhD

CONTACT

27666417; kyeva.ho@polyu.edu.hk

Ka Wai Lam, PhD

CONTACT

27666420; kwkatlam@polyu.edu.hk

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: May 3, 2021
• First Posted: May 17, 2021
• Study Start: September 1, 2021
• Primary Completion: September 1, 2024
• Study Completion: September 1, 2024
• Last Updated: April 19, 2022

Record last verified: 2022-04

Data Sharing

• IPD Sharing: Will not share

Locations

HK (1)