Investigation of the Efficacies of Multi Berries Juice on Anti Oxidant Effect and Improvement of Skin Conditions

NCT04878523 | Completed

• 1 other identifier: 20-082-B
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

To assess multi berries juice on anti-oxidant effect and skin condition improvement

Conditions

Skin Condition; Anti Oxidative Stress

Outcome Measures

Primary Outcomes (7)

• The change of skin UV spots

  VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units

  Change from Baseline skin UV spots at 8 weeks

• The change of skin melanin index

  Soft Plus was utilized to measure skin melanin index. Units: arbitrary units

  Change from Baseline skin melanin index at 8 weeks

• The change of blood SOD content

  Venous blood was sampled to measure concentrations of SOD

  Change from Baseline SOD content at 8 weeks

• The change of blood total antioxidant capacity (TAC)

  Venous blood was sampled to measure concentrations of TAC

  Change from Baseline TAC at 8 weeks

• The change of skin L* value

  Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units, 0-100

  Change from Baseline L* value at 8 weeks

• The change of skin spots

  VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units

  Change from Baseline skin spots at 8 weeks

• The change of skin brown spots

  VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units

  Change from Baseline skin brown spots at 8 weeks

Secondary Outcomes (7)

• The change of skin moisture

  Change from Baseline skin moisture at 4 weeks

• The change of skin a* value

  Change from Baseline a* value at 8 weeks

• The change of skin elasticity

  Change from Baseline skin elasticity at 8 weeks

• The change of skin wrinkles

  Change from Baseline skin wrinkles at 8 weeks

• The change of skin texture

  Change from Baseline skin texture at 8 weeks

Other Outcomes (7)

• The change of total cholesterol of blood

  Change from Baseline total cholesterol at 8 weeks

• The change of triglyceride of blood

  Change from Baseline triglyceride at 8 weeks

• The change of SGOT of blood

  Change from Baseline SGOT at 8 weeks

Study Arms (2)

Placebo drink

PLACEBO COMPARATOR

Dietary Supplement: Placebo drink

multi berries juice

EXPERIMENTAL

Dietary Supplement: multi berries juice

Interventions

multi berries juice DIETARY_SUPPLEMENT

Testing product

Also known as: Sei Bella™ Pure Essence Whitening Multi-Berries Drink

multi berries juice

Placebo drink DIETARY_SUPPLEMENT

Blank

Placebo drink

Eligibility Criteria

• Age: 20 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy adults aged above 20 years old

You may not qualify if:

• Subject who is not willing to participate in this study.
• Patients with diseases of the skin, liver, kidney.
• Subjects who have known cosmetic, drug or food allergies, difficulty in digestive tract absorption or disorder.
• Female who is pregnant or nursing or planning to become pregnant during the course of the study.
• Received facial laser therapy, chemical peeling or UV overexposure in the past 4 weeks.
• Constant drug use

Sponsors & Collaborators

• TCI Co., Ltd.: lead

Study Sites (1)

Chia Nan University of Pharmacy & Science

Tainan, 71710, Taiwan

Location

MeSH Terms

Conditions

Skin Diseases

Condition Hierarchy (Ancestors)

Skin and Connective Tissue Diseases

Study Officials

• Chia-Hua Liang

  Chia Nan University of Pharmacy ＆ Science

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: INDUSTRY
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 6, 2021
• First Posted: May 7, 2021
• Study Start: November 9, 2020
• Primary Completion: January 15, 2021
• Study Completion: February 25, 2021
• Last Updated: May 7, 2021

Record last verified: 2021-05

Locations

TW (1)