NCT04870086

Brief Summary

ESPERES is a national prospective e-cohort study providing a resource for collecting information on healthcare workers (HCWs) currently working in France. The overall goal of ESPERES is to develop the infrastructure necessary to create and engage a community of HCWs who may be eligible for participation in future research studies. ESPERES is set up to answer research questions, in the field of prevention for HCWs, prevention for their own health, that of their relatives, their colleagues, and users of the hospital. These research questions will be carried out in the context of specific subsequent studies. The first study that will be carried out is related to prevention against COVID-19, in particular vaccination against COVID-19 and more broadly on the COVID-19 pandemic.

Trial Health

57
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
15,000

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Apr 2021

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 6, 2021

Completed
2 days until next milestone

First Submitted

Initial submission to the registry

April 8, 2021

Completed
25 days until next milestone

First Posted

Study publicly available on registry

May 3, 2021

Completed
1.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2022

Completed
3.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

April 23, 2026

Completed
Last Updated

June 21, 2022

Status Verified

June 1, 2022

Enrollment Period

1.5 years

First QC Date

April 8, 2021

Last Update Submit

June 17, 2022

Conditions

Healthcare Workers

Keywords

Healthcare workersPreventive measuresAttitudes

Outcome Measures

Primary Outcomes (6)

  • Number and percent of participants who enroll in the ESPERES cohort study by age.

    Up to 24 months

  • Number and percent of participants who enroll in the ESPERES cohort study by health establishment.

    Up to 24 months

  • Number and percent of participants who enroll in the ESPERES cohort study by geographic region

    Up to 24 months

  • Number and percent of participants who enroll in the ESPERES cohort study by profession

    Up to 24 months

  • Proportion of all participants enrolled in the ESPERES cohort study who participate in an ancillary research study

    Up to 24 months

  • Proportion of participants who continue to supple information about their health to the ESPERES cohort study at various time points after their enrollment

    Up to 24 months

Eligibility Criteria

Age18 Years - 99 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will be made up of HCWs. For the purposes of this study, a "healthcare worker" is defined as an individual who currently works in a setting where individuals receive healthcare (i.e. individuals do not have to work directly with patients, but may have any role within a setting where individuals receive healthcare, such as administrative office, housekeeping, food service, etc.). ESPERES will be offered to all the HCWs of the Assistance Publique - Hôpitaux de Paris (AP-HP) establishments and to other public or private health establishments (lucrative or not) in the Ile-De-France region and to establishments in other French regions, in order to diversify the contexts.

You may qualify if:

  • Legal age
  • Healthcare workers defined as individuals who currently work in a setting where individuals receive healthcare (i.e. individuals do not have to work directly with patients, but may have any role within a setting where individuals receive healthcare, such as administrative office, housekeeping, food service, etc.)
  • Agreeing to participate (digital consent)

You may not qualify if:

  • \- No internet access

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Pitié-Salpêtrière - Charles Foix, AP-HP

Paris, 75013, France

RECRUITING

Related Publications (1)

  • Ricci L, Fery C, Tubach F, Agrinier N, Gagneux-Brunon A. Health care institutions and their physicians are the greatest promoters of COVID-19 vaccine acceptance among health care workers. Vaccine. 2025 Apr 30;54:127005. doi: 10.1016/j.vaccine.2025.127005. Epub 2025 Mar 14.

    PMID: 40088510DERIVED

MeSH Terms

Conditions

Behavior

Study Officials

  • Florence Tubach, MD, PHD

    Assistance Publique - Hôpitaux de Paris

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Florence Tubach, MD, PHD

CONTACT

01 42 16 05 88florence.tubach@aphp.fr

Sandra Fournier, MD

CONTACT

sandra.fournier@aphp.fr

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 8, 2021

First Posted

May 3, 2021

Study Start

April 6, 2021

Primary Completion

October 1, 2022

Study Completion

April 23, 2026

Last Updated

June 21, 2022

Record last verified: 2022-06

Locations

FR(1)