Risk Profiling of the Occupational Exposure of COVID-19 to Healthcare Workers.

NCT04477213 | Completed

• 1 other identifier: NMCHCW-COVID
• Study Type: observational
• Target: 286
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators propose to conduct a retrospective study to define and quantify the variable occupational and non-occupational risk among various HCWs who got COVID-19 . The investigators aim to determine the rates of acquisition of COVID-19, in the context of level of exposure , adequacy of PPE use and other infection control measuresrecommended for COVID-19 and also to define the risk of secondary disease transmission to other household members of HCWs.

Conditions

COVID19; Healthcare Workers

Keywords

COVID-19; Healthcare Workers; occupational risk of COVID-19

Outcome Measures

Primary Outcomes (1)

• Rate of COVID-19 in healthcare workers (HCWs)

  Positive HCW divided by total exposed HCWs in that category X 100 Rate will be calculated in 4 different categories. 1. Front line HCWs (doctors, nurses, respiratory therapist, physiotherapist, dialysis technician, patient assistant etc) 2. Front line support staffs (Customer care, pharmacist, billing assistance, ambulance driver etc.), 3. Clinical support staffs- (dietician, food service worker, laundry worker, housekeeping staffs, health record staffs- infection control team etc.) 4. Non-clinical support staffs- (Administrative support staff.)

  6 months

Secondary Outcomes (1)

• clinical severity of infection in HCWs

  Within 28 days of illness.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All Healthcare workers working actively in the included hospitals or clinics and are confirmed positive with COVID-19

You may qualify if:

• All staffs that are currently working in included hospitals and clinic in 1.2.1.1 Laboratory confirmed positive case- A positive case is where COVID-19 virus is detected through real time polymerase chain reaction (RT PCR) either through oropharyngeal or nasopharyngeal swab which were conducted on HCWs based on national guidelines of UAE and are based on either symptoms, or as part of contact tracing or history of recent international travel.
• Laboratory confirmed positive case with history of occupational exposure- through contact tracing after an exposure to a known COVID -19 patient in a healthcare setting.
• Laboratory confirmed positive case with no history of occupational exposure- non-occupational exposures include situations where there was no probable workplace exposure for the healthcare worker, and a community source for the infection through household contact, travel, gathering in public places or visiting to affected area as most likely source of exposure is identified.

You may not qualify if:

• Staff who refused to participate or withdraw there consent during the study.

Sponsors & Collaborators

• NMC Specialty Hospital: lead

Study Sites (1)

NMC Specialty Hospital, Al Nahda

Dubai, United Arab Emirates

Location

Related Publications (2)

• Nguyen LH, Drew DA, Joshi AD, Guo CG, Ma W, Mehta RS, Sikavi DR, Lo CH, Kwon S, Song M, Mucci LA, Stampfer MJ, Willett WC, Eliassen AH, Hart JE, Chavarro JE, Rich-Edwards JW, Davies R, Capdevila J, Lee KA, Lochlainn MN, Varsavsky T, Graham MS, Sudre CH, Cardoso MJ, Wolf J, Ourselin S, Steves CJ, Spector TD, Chan AT. Risk of COVID-19 among frontline healthcare workers and the general community: a prospective cohort study. medRxiv [Preprint]. 2020 May 25:2020.04.29.20084111. doi: 10.1101/2020.04.29.20084111.

  PMID: 32511531 RESULT

• Wu Z, McGoogan JM. Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in China: Summary of a Report of 72 314 Cases From the Chinese Center for Disease Control and Prevention. JAMA. 2020 Apr 7;323(13):1239-1242. doi: 10.1001/jama.2020.2648. No abstract available.

  PMID: 32091533 RESULT

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Study Officials

• Helen King, RN DMS MBA

  Senior Vice President: Nursing & Quality Corporate Quality & Nursing

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Specialist Critical Care Medicine

Study Record Dates

• First Submitted: July 17, 2020
• First Posted: July 20, 2020
• Study Start: September 11, 2021
• Primary Completion: September 30, 2021
• Study Completion: October 2, 2021
• Last Updated: October 11, 2021

Record last verified: 2021-09

Locations

AE (1)