Classifying and Predicting Long-term Pain and Function in Older Adults

NCT04864223 | Completed

• 1 other identifier: STUDY00005507
• Study Type: observational
• Target: 6,783
• Locations: 1 country
• Sites: 1

Brief Summary

This project will use novel methods to detect clinically meaningful subgroups of older adults based on long-term trajectories of bothersome pain and function. It will then identify older adults at high risk of experiencing poor long-term pain and function. Anticipated results will provide new insights into long-term patterns of pain and function across the aging process and identify potential predictors of each trajectory.

Conditions

Chronic Pain; Pain

Keywords

older adults; chronic pain; function; physical performance

Outcome Measures

Primary Outcomes (2)

• Bothersome Pain

  Question: "In the last month, have you been bothered by pain?" Dichotomous response of yes or no

  6 years

• Physical Performance

  Short Physical Performance Battery (SPPB). Scored from 0=worst to 12=best based on 3 performance tests: walking, chairs stands, and balance tasks

  6 years

Secondary Outcomes (2)

• Activity Limitations Due to Pain

  6 years

• Functional Capacity

  6 years

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

NHATS is a cohort of older adults and is representative of Medicare beneficiaries age 65 years and older. It is a "unique national resource for the scientific study of functioning in later life." The sample is drawn from the Medicare enrollment files, and the survey oversamples Blacks and those at older ages. NHATS data collection began in 2011 (Round 1) with in-person interviews. Participants were re-interviewed yearly (Rounds 2-7). This is a unique cohort because it contains comprehensive survey data in addition to physical performance measures for individuals over multiple years. During each round, NHATS collects a wide array of information during the interviews, including: demographic, health, social, economic, environmental, cognitive, behavioral, and physical data.

You may qualify if:

• community-dwelling older adults from Round 1 of the NHATS cohort

You may not qualify if:

• participants who are non-ambulatory (require a wheelchair or scooter for mobility) at Round 1

Sponsors & Collaborators

• University of Washington: lead
• University of Pittsburgh: collaborator

Study Sites (1)

University of Washington

Seattle, Washington, 98105, United States

Location

MeSH Terms

Conditions

Chronic Pain; Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: August 14, 2019
• First Posted: April 28, 2021
• Study Start: August 1, 2018
• Primary Completion: July 31, 2020
• Study Completion: July 31, 2020
• Last Updated: April 28, 2021

Record last verified: 2021-04

Data Sharing

• IPD Sharing: Will share

Locations

US (1)