The Impact of Music Therapy on Nociceptive Processing

NCT03692247 | Completed

• 1 other identifier: 2017P002872
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The purpose of this study is to understand the use of brief, personalized music interventions to decrease pain. Persisting and recurring pain is devastating to individuals and society. The worry and anxiety people feel while experiencing chronic pain may increase how much pain they feel. Enjoyable music feels good and affects brain chemicals in a way that can lessen feelings of pain. Music that feels good can also lower the anxiety and worry that accompany chronic pain which may play a role in the pain relief music provides.

Conditions

Pain; Chronic Pain

Keywords

pain; music

Outcome Measures

Primary Outcomes (1)

• Changes in Pain Sensitivity in the Presence of Music

  Change in pain sensitivity, measured as a difference in the temporal summation of pain with a mechanical stimulus between a control and music condition of testing.

  40 minutes

Study Arms (1)

Quantitative Sensory Testing

OTHER

After answering brief questionnaires assessing psychosocial factors related to anxiety, catastrophizing, and pain, participants will undergo quantitative sensory tests where they will use a simple numeric rating scale (0-10) to rate pain and anxiety at several points during two QST sessions. During the second QST session, participants will use Unwind, a smartphone-based music intervention.

Other: Smartphone-based Music Intervention

Interventions

Smartphone-based Music Intervention OTHER

The smartphone-based music intervention (Unwind) is a music protocol that gathers basic information from the patient including a 0-10 pain scale and 0-10 anxiety scale as well as recorded heart rate. Using these variables, a machine learning protocol pieces together a music intervention between 5-20 minutes long. The duration of the intervention can be controlled by the patient or experimenter. No identifying data is kept on the smartphone.

Quantitative Sensory Testing

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Over 18 years old
• Able to sign English written consent
• No history of chronic opioid use (have an opioid prescription more than 30 days).

You may not qualify if:

• Under 18 years old
• Non-English speaking
• Unwilling to undergo quantitative sensory testing
• Hearing loss
• Diagnosis of neuropathy
• History of chronic opioid use (having an opioid prescription more than 30 days).

Sponsors & Collaborators

• Brigham and Women's Hospital: lead

Study Sites (1)

Brigham and Women's Hospital

Brookline, Massachusetts, 02115, United States

Location

MeSH Terms

Conditions

Pain; Chronic Pain

Condition Hierarchy (Ancestors)

Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• Edward Boyer, MD, PhD

  Brigham and Women's Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director of Academic Development

Model Details: This is a cohort study of one group of 60 healthy volunteers without a diagnosis of neuropathy or chronic pain.

Study Record Dates

• First Submitted: June 16, 2018
• First Posted: October 2, 2018
• Study Start: June 7, 2018
• Primary Completion: July 18, 2018
• Study Completion: July 18, 2018
• Last Updated: January 30, 2019

Record last verified: 2019-01

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)