NCT00409552

Brief Summary

A number of studies have shown that virtual reality (VR) can be used to distract patients from pain and anxiety during painful medical procedures for which medication provides inadequate relief. An inexpensive, commercially available VE could have significant impact in reducing perceived pain involved in a variety of medical procedures. The Virtual Reality Medical Center (VRMC) developed an engaging virtual world that proved to be effective in reducing reported pain ratings of participants experiencing several different forms of painful stimuli. The virtual world called Icy Cool World was found to successfully distract patients from painful stimuli and reduce patients' perceived levels of pain. Phase II looks to expand on these findings and examine the effectiveness as a pain distraction technique for a variety of acute and chronic pain etiologies. The main objective of the clinical investigation will be to expand on the findings from earlier studies and obtain a more comprehensive analysis regarding the clinical versatility of VR pain distraction.

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
10

participants targeted

Target at below P25 for phase_1 pain

Timeline
Completed

Started Nov 2009

Typical duration for phase_1 pain

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 8, 2006

Completed
3 days until next milestone

First Posted

Study publicly available on registry

December 11, 2006

Completed
2.9 years until next milestone

Study Start

First participant enrolled

November 1, 2009

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2010

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2010

Completed
Last Updated

January 12, 2017

Status Verified

September 1, 2009

Enrollment Period

1.1 years

First QC Date

December 8, 2006

Last Update Submit

January 11, 2017

Conditions

Outcome Measures

Primary Outcomes (1)

  • Pain rating reduction

    Following each trial

Study Arms (5)

1

EXPERIMENTAL

Virtual Reality with head display

Behavioral: Virtual Reality based distraction

2

ACTIVE COMPARATOR

Virtual Reality with flat projection display

Behavioral: VR with flat projection display

3

ACTIVE COMPARATOR

non-interactive video with head display

Behavioral: non-interactive video with head display

4

ACTIVE COMPARATOR

non-interactive video with flat projection display

Behavioral: non-interactive video with with flat projection display

5

NO INTERVENTION

No distraction

Interventions

Participants will undergo virtual reality based distraction using the head display while they go through the pain process.

1

VR with flat projection display

2

non-interactive video with head display

3

non-interactive video with with flat projection display

4

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18-65, male or female, any ethnicity as long as candidates can understand and read English adequately.

You may not qualify if:

  • We will exclude participants who meet DSM-IV-TR criteria for alcohol or other substance abuse in the past year, or are currently using any recreational drugs, or taking more than 20 alcoholic drinks a week. In addition, the Beck Depression Inventory II (BDI-II) score must be less than 16, with no suicidal ideation.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

PainChronic Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Mark D Wiederhold, MD, PhD, FACP

    VRMC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
SUPPORTIVE CARE
Intervention Model
PARALLEL
Sponsor Type
NIH
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 8, 2006

First Posted

December 11, 2006

Study Start

November 1, 2009

Primary Completion

December 1, 2010

Study Completion

December 1, 2010

Last Updated

January 12, 2017

Record last verified: 2009-09