Effect of Interval Training on Arterial Stiffness in Women With Hypertension
1 other identifier
interventional
50
1 country
1
Brief Summary
this study is aiming to assess the chronic effect of the interval training program on arterial stiffness in women with hypertension
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Jan 2021
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
January 12, 2021
CompletedStudy Start
First participant enrolled
January 25, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
April 15, 2021
CompletedFirst Posted
Study publicly available on registry
April 28, 2021
CompletedMarch 15, 2022
March 1, 2022
2 months
January 12, 2021
March 14, 2022
Conditions
Outcome Measures
Primary Outcomes (1)
Central arterial stiffness measurements (Pulse Wave Velocity [PWV], augmentation index )
Pulse wave analysis (PWA) of the women in the two groups: pre and post treatment for pulse wave velocity (PWV) and augmentation index(AIx) Pulse Wave Velocity \[PWV\], augmentation index (AIx @75HR) and resting heart rate were measured using analysis equipment which called Non-invasive blood pressure measurement system using "Mobil-O-Graph 24h PWA " with Hypertension Management Software Client Server (HMS-CS 4.3). PWA was performed using an oscillometric Mobil-O-Graph R 24 h PWA Monitor device (I.E.M GmbH, Germany) with integrated ARCSolver® software
two months
Secondary Outcomes (3)
blood lipid profile
two months
interleukin 6
two months
blood pressure (systolic and diastolic)
two months
Study Arms (2)
interval training
EXPERIMENTALAerobic interval training. It consisted of a modified interval cycle ergometer training program (3 days a week for 8 weeks). AIT consisted of 8 min warm up, followed by four times of 4-min intervals with HR at 80% of submaximal predetermined HR, with active phases of 3 min of cycling at 60% of submaximal predetermined HR. The exercise session was terminated by 5 min cool down
medical treatment
NO INTERVENTIONhypertensive medication
Interventions
Eligibility Criteria
You may qualify if:
- physically inactive
- BMI 30-40
- Stage 1 and 2 hypertension
- Elevated BP as systolic BP ≥130 mm Hg and/or diastolic BP ≥85 mm Hg measured at the brachial artery.
You may not qualify if:
- Medications known to affect weight or appetite
- Any disease associated with exercise intolerance.
- Women were taking hormone replacement therapy
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Cairo Universitylead
Study Sites (1)
Faculty of physical therapy
Cairo, 17452, Egypt
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Cairo University
Study Record Dates
First Submitted
January 12, 2021
First Posted
April 28, 2021
Study Start
January 25, 2021
Primary Completion
March 30, 2021
Study Completion
April 15, 2021
Last Updated
March 15, 2022
Record last verified: 2022-03