DBT Skills Plus EMDR for BPD and Trauma

NCT04856449 | Unknown

• 1 other identifier: IIBSP-TLP-2020-105
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

Borderline Personality Disorder (BPD) is a severe disorder that frequently co-occurs with post-traumatic stress disorder (PTSD). The comorbidity of BPD and PTSD is more disabling, predicting lower rates of BPD remission. Dialectical behavioral skills training (DBT-ST), is a group-delivered training that covers four types of skills: emotion regulation, mindfulness, interpersonal effectiveness and distress tolerance. As a stand-alone treatment, research suggest that DBT-ST is an efficacious treatment for BPD. In parallel, EMDR has emerged in last years as an efficacious approach to adult trauma. However, so far, the efficacy of EMDR to treat trauma in populations with BPD diagnosis has not been tested. The present pilot randomized-controlled clinical trial aims to test whether a combination of DBT-ST plus EMDR could be efficacious to treat trauma in individuals with BPD. 40 participants will be recruited from the BPD Unit at the Hospital de la Santa Creu I Sant Pau (Barcelona, Spain) and will be randomized (1:1) to DBT-ST + EMDR or DBT-ST alone. The primary outcome will be the reduction of PTSD symptoms. In addition, symptom-related variables will be collected before and after the interventions. This will be the first study to test the combination of DBT-ST and EMDR.

Conditions

Borderline Personality Disorder; Trauma

Outcome Measures

Primary Outcomes (1)

• Borderline Symptom List 23 (BSL-23)

  The scores range from a 0 to 4, with higher scores indicating a worse outcome.

  1 week

Secondary Outcomes (3)

• Impact of Events Scale Revised

  1 week

• Patient Health Questionnaire (PHQ-9)

  2 weeks

• DISSOCIATIVE EXPERIENCES SCALE (DES)

  1 month

Study Arms (2)

DBT Skills Training

EXPERIMENTAL

This intervention will consist of a 6-month-group DBT-skills training continuation, in which participants will be trained in mindfulness, emotion regulation, distress tolerance and interpersonal effectiveness.

Behavioral: Dialectical Behavioral Therapy Skills Training

Eye Movement Desensitization and Reprocessing (EMDR)

ACTIVE COMPARATOR

EMDR will consist of individual therapy sessions that will be focused on processing traumatic memories. Participants will receive up to 16 individual EMDR sessions, of 60 min each.

Behavioral: EMDR

Interventions

Dialectical Behavioral Therapy Skills Training BEHAVIORAL

DBT skills training consists of a 6 months training in mindfulness, emotion regulation, interpersonal effectiveness and distress tolerance.

Also known as: DBT-ST

DBT Skills Training

EMDR BEHAVIORAL

EMDR sessions will be conducted to reprocess trauma-related memories.

Eye Movement Desensitization and Reprocessing (EMDR)

Eligibility Criteria

• Age: 18 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• men and women between 18 and 60 years old
• having had adverse childhood experiences and/or current PTSD symptoms
• signed informed consent

You may not qualify if:

• lifetime diagnosis of schizophrenia, drug-induced psychosis, organic brain syndrome, bipolar disorder, or mental retardation.
• participation in any psychotherapy during the study or having received DBT or EMDR in the past

Sponsors & Collaborators

• Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau: lead
• EMDR Europe: collaborator

Study Sites (1)

Hospital de la Santa Creu i Sant Pau

Barcelona, Catalonia, 08025, Spain

RECRUITING

MeSH Terms

Conditions

Borderline Personality Disorder; Wounds and Injuries

Interventions

Eye Movement Desensitization Reprocessing

Condition Hierarchy (Ancestors)

Personality Disorders; Mental Disorders

Intervention Hierarchy (Ancestors)

Desensitization, Psychologic; Behavior Therapy; Psychotherapy; Behavioral Disciplines and Activities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: April 8, 2021
• First Posted: April 23, 2021
• Study Start: September 6, 2021
• Primary Completion: May 1, 2023
• Study Completion: May 1, 2023
• Last Updated: March 16, 2023

Record last verified: 2023-03

Data Sharing

• IPD Sharing: Will not share

Locations

ES (1)