Psychoeducational Videos and Digital Assessments for BPD

NCT05358925 | Completed

• 2 other identifiers: 2022P00089230053
• Study Type: interventional
• Target: 83
• Locations: 1 country
• Sites: 1

Brief Summary

In this study, 100 adults who were recently diagnosed with borderline personality disorder (BPD) will be randomized to either receive educational videos about BPD or educational videos about other topics. All participants in both conditions will complete daily surveys about their emotions and social interactions, and they will respond to surveys and complete cognitive tests at 4 different time points. Some participants will receive feedback about their cognitive test performance, and others will not. The investigators are interested in learning about how accurate education about BPD and enhanced knowledge about cognitive abilities might help people manage their BPD symptoms. The investigators expect that participants who received psychoeducation about BPD will have lower levels of BPD and depressive symptoms than other participants, and that participants who received feedback on their cognitive tests will also have lower symptoms.

Conditions

Borderline Personality Disorder

Keywords

borderline personality disorder; ecological momentary assessment; psychoeducation; neuropsychological feedback; symptom tracking

Outcome Measures

Primary Outcomes (1)

• Borderline Symptom List 23 (BSL-23)

  Change (increase or decrease) in BSL-23 mean score (average score across all 23 items) at time 2, time 3, and follow-up, as compared to baseline. Minimum score = 0, maximum score = 4. A higher score indicates more severe BPD symptoms.

  Baseline (day 1), Time 2 (day 15), Time 3 (day 30), Follow-Up (day 60)

Secondary Outcomes (1)

• Patient Health Questionnaire (PHQ-9)

  Baseline (day 1), Time 2 (day 15), Time 3 (day 30), Follow-Up (day 60)

Other Outcomes (14)

• Treatment History Questionnaire

  Baseline (day 1), Follow-Up (day 60)

• BPD Knowledge Assessment

  Baseline (day 1), Time 2 (day 15), Follow-Up (day 60)

• Hospitalization Check-In

  Time 2 (day 15) and Time 3 (day 30)

Study Arms (3)

BPD Videos and Feedback

EXPERIMENTAL

Ten daily 4-10 minute psychoeducational videos about BPD and personalized feedback about performance on neuropsychological tasks.

Other: Psychoeducational Videos; Other: Neuropsychological Feedback

BPD Videos and No Feedback

EXPERIMENTAL

Ten daily 4-10 minute psychoeducational videos about BPD.

Other: Psychoeducational Videos

Non-BPD Videos and No Feedback

SHAM COMPARATOR

Ten daily 4-10 minute educational videos about health-related topics other than BPD.

Other: Non-BPD-related Educational Videos

Interventions

Psychoeducational Videos OTHER

A total of ten videos will be delivered daily Monday-Friday over approximately 2 weeks (days 1-15). The videos will each feature a mental health professional who is an expert in BPD explaining the topic in relatable language that can be understood by the general public. Each video will be approximately 4-10 minutes long, for a total of \~72 minutes of video. Videos will be shared via a hyperlink in a text message. The psychoeducational videos will cover the following topics: symptoms, basic factors about BPD, the naturalistic long term course of BPD, prevalence of BPD and its common comorbid disorders, key principles for recovery, available psychotherapeutic treatment options for BPD, common factors amongst treatments, medications, the interpersonal hypersensitivity model of BPD, and a review of the top 10 tips.

BPD Videos and Feedback; BPD Videos and No Feedback

Neuropsychological Feedback OTHER

In the second phase of the study, participants randomized to the Feedback condition will receive an email with a personalized summary of their symptom endorsement and neuropsychological performance. The feedback will include the relevant scores or sub-scores for each cognitive test (CPT, RMET, BEST, DST) from the first two time points. For each score and sub-score, there will be a description of the cognitive domain that the metric assesses (e.g., attention span in the CPT). The investigators will tailor the feedback to each participant's scores. The investigators may adjust the format or wording of the feedback based on participant responses (i.e., if a participant alerts the investigators that some wording is unclear or confusing). The investigators may also alter the feedback if they learn new information about the relevance or interpretability of these cognitive tests, as this is a growing field of research.

BPD Videos and Feedback

Non-BPD-related Educational Videos OTHER

The non-BPD-related educational videos will be matched in length and frequency to the BPD-related videos. These videos will discuss aspects of mental and physical health that are not related to BPD. Examples may include: nutrition and healthy eating, coping, self-compassion and self-care, stress and anxiety, depression, and healthy sleep habits.

Non-BPD Videos and No Feedback

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• reliable access to a smartphone with a data plan for the duration of the study
• ability to speak and understand English
• age 18 years or older
• diagnosis of BPD within the past 6 months
• awake and able to complete EMA surveys between 9:00am and 9:00pm on most days
• located within the United States

You may not qualify if:

• cognitive disability that impedes ability to participate in the study
• current psychiatric symptoms that interfere with the individual's ability to provide consent or complete the research procedures (e.g., acute mania, acute psychosis, eating disorder threatening medical stability).

Sponsors & Collaborators

• Mclean Hospital: lead
• Brain & Behavior Research Foundation: collaborator

Study Sites (1)

McLean Hospital

Belmont, Massachusetts, 02478, United States

Location

Related Publications (1)

• Choi-Kain LW, Murray GE, Jurist J, Ren B, Germine L. Online psychoeducation and digital assessments as a first step of treatment for borderline personality disorder: A protocol for a pilot randomized controlled trial. PLoS One. 2023 Dec 7;18(12):e0294331. doi: 10.1371/journal.pone.0294331. eCollection 2023.

  PMID: 38060545 DERIVED

MeSH Terms

Conditions

Borderline Personality Disorder

Condition Hierarchy (Ancestors)

Personality Disorders; Mental Disorders

Study Officials

• Lois W Choi-Kain, MD

  Mclean Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Masking Details: While the investigators will not explicitly inform participants of their condition, it will be apparent based on the content of the videos they receive and whether or not they receive feedback. The investigators and study staff will be aware of condition assignments in order to facilitate the delivery of the appropriate videos and the neuropsychological feedback.
• Purpose: TREATMENT
• Intervention Model: SEQUENTIAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director, Gunderson Personality Disorder; Associate Professor of Psychiatry

Model Details: This study includes two randomization branching points: (1) BPD-related videos vs. non-BPD-related videos, and (2) receive neuropsychological feedback vs. not. At branching point (1), 2/3 of participants will be directed to the BPD-video condition, and 1/3 to the non-BPD-video condition. Only the participants in the BPD-video condition will be randomized to receive feedback or not (1/2 each condition). No non-BPD-video participants will receive feedback.

Study Record Dates

• First Submitted: April 28, 2022
• First Posted: May 3, 2022
• Study Start: June 1, 2023
• Primary Completion: August 20, 2024
• Study Completion: December 1, 2025
• Last Updated: January 6, 2026

Record last verified: 2025-12

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)