Fluid Replacement in Bariatric Surgery

NCT04855318 | Completed

• 1 other identifier: 09.2020.158
• Study Type: observational
• Target: 2
• Locations: 1 country
• Sites: 1

Brief Summary

The frequency of obese postoperative rhabdomyolized acute tubular necrosis (ATN) and renal failure is also increasing. It is simply important to manage fluid. The fluid requirement should be higher than planned. In order to learn the postoperative ATN and the development of renal failure, 4-5 lt crystalloid fluid should be given in 2-3 times or 1.5 ml / kg / h should be provided in the upper outlet. According to TVA, there are no good guidelines for intraoperative fluid management in bariatric surgery. Different intraoperative fluid management communications are used. The key to improving outcomes from post-operative treatment is "patient directed fluid management" or "targeted fluid management". The use of Perioperative Goal-Directed Fluid Therapy Technologies helps the anesthesiologist closely monitor the patient and strike the delicate balance between benefit and risk. Plethysmographic variability index monitoring (PVI-Pleth Variability Index) is a non-invasive, automatic and continuous monitor that displays patient fluid response, it is one of the easily applicable and easily interpreted monitoring methods. With PVI monitoring, intraoperative hypotension and fluid need can be predicted in advance. Plethysmographic Variability Index (PVI) is the determination of the importance of monitoring of intraoperative volume replacement and its effect on postoperative operations.

Conditions

Obesity

Keywords

obesity; fluid therapy; pleth variability index

Outcome Measures

Primary Outcomes (1)

• Fluid therapy in bariatric patients

  Fluid therapy is providewith pleth variability index monitorisation

  during surgery

Eligibility Criteria

• Age: 18 Years - 64 Years
• Sex: all
• Age Groups: Adult (18-64)
• Sampling Method: Probability Sample

Study Population

sample size 60

You may qualify if:

• obese patients who scheduled for elective bariatric surgery

You may not qualify if:

• severe cardiac arrhythmia
• peripheral artery disease
• an ejection fraction \<30%
• any pulmonary pathology preventing a respiratory volume \>6 ml/kg/min on mechanical ventilation
• hepatic or renal impairment

Sponsors & Collaborators

• Marmara University: lead

Study Sites (1)

Marmara University

Istanbul, Maltepe, 34854, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Obesity

Condition Hierarchy (Ancestors)

Overweight; Overnutrition; Nutrition Disorders; Nutritional and Metabolic Diseases; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Officials

• MELIHA ORHON ERGUN

  Marmara University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: assistant professor

Study Record Dates

• First Submitted: April 4, 2021
• First Posted: April 22, 2021
• Study Start: January 10, 2021
• Primary Completion: March 10, 2021
• Study Completion: March 20, 2021
• Last Updated: March 31, 2022

Record last verified: 2021-06

Locations

TU (1)