Acute Consumption of Pecan-enriched Meal
Comparison of Metabolic and Antioxidant Responses to a Breakfast Meal With and Without Pecans
1 other identifier
interventional
24
1 country
1
Brief Summary
Pecans are a nutrient-dense food, but it is unknown whether substituting pecans for a portion of the butter in a traditional breakfast meal improves post-meal responses.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable healthy
Started Aug 2017
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 10, 2017
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 27, 2018
CompletedStudy Completion
Last participant's last visit for all outcomes
February 27, 2018
CompletedFirst Submitted
Initial submission to the registry
April 7, 2021
CompletedFirst Posted
Study publicly available on registry
April 20, 2021
CompletedApril 20, 2021
April 1, 2021
7 months
April 7, 2021
April 13, 2021
Conditions
Outcome Measures
Primary Outcomes (4)
Change in triglycerides (TG) and glucose
TG (mg/dL) and glucose (mg/dL)
Change from baseline to 3 hours postprandially
Change in lipid peroxidation
Malondialdehyde (MDA) (uM) measured via Thiobarbituric acid reactive substances (TBARS) assay
Change from baseline to 3 hours postprandially
Change in total antioxidant capacity
Total antioxidant capacity (uM trolox equivalents) measured via Oxygen Radical Absorbance Capacity (ORAC) assay.
Change from baseline to 3 hours postprandially
Change in insulin
Insulin (uU/mL)
Change from baseline to 3 hours postprandially
Secondary Outcomes (2)
Change in angiopoietin-like proteins-3 (ANGPTL3) and -4 (ANGPTL4) responses
Change from baseline to 3 hours postprandially
Change in hunger and satiety responses
Change from baseline to 3 hours postprandially
Study Arms (2)
Control
ACTIVE COMPARATORParticipants in this group received a traditional muffin with butter as the predominant source of fat.
Pecan
EXPERIMENTALParticipants in this group received a muffin in which part of the butter was substituted out for pecans.
Interventions
Eligibility Criteria
You may qualify if:
- Healthy adult men and women
- Normal-weight (body mass index = 18-24.9kg/m2)
You may not qualify if:
- Allergies to test meal ingredients (gluten, eggs, or nuts)
- Medication/supplement usage
- Chronic disease
- Pregnancy or plans to become pregnant
- Special diets
- Tobacco use
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of Georgia - Department of Foods and Nutrition & Department of Food Science and Technology
Athens, Georgia, 30602, United States
Study Officials
- PRINCIPAL INVESTIGATOR
Chad M Paton, PhD
University of Georgia
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- SINGLE
- Who Masked
- PARTICIPANT
- Purpose
- OTHER
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Professor and Director of UGA Obesity Initiative
Study Record Dates
First Submitted
April 7, 2021
First Posted
April 20, 2021
Study Start
August 10, 2017
Primary Completion
February 27, 2018
Study Completion
February 27, 2018
Last Updated
April 20, 2021
Record last verified: 2021-04
Data Sharing
- IPD Sharing
- Will not share