Pathway to Detection & Differentiation of Delirium & Dementia in the Emergency Department

NCT04846322 | Completed Results DMC

• 2 other identifiers: 2000029490U54AG063546
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 2

Brief Summary

This is an observational study of the pragmatic implementation of an ED screening, outpatient referral, and care coordination process for older ED patients who may have UCID.

Conditions

Cognitive Impairment; Emergency Care; Dementia; Delirium

Keywords

delirium

Outcome Measures

Primary Outcomes (4)

• Percentage of Patients With Confirmed Delirium or Dementia

  percentage of patients discharged from ED positive for delirium or dementia among total number of patients 65+

  1 year

• Rates of Outpatient Assessment Referral of Patients With Suspected Dementia

  number of patients with appointment to Alzheimer's Dementia Centers or geriatrics outpatient clinic / number of patients given information sheet or referred to outpatient clinic

  30 days

• Number of Participants Diagnosed With Dementia Among Those With Completed Outpatient Assessment

  number of patients diagnosed with dementia (all categories) among those that completed the outpatient assessment

  Up to 100 days from ED discharge

• Rates of Connection With Primary Care

  number of patients with PCP follow-up about brain health plan of the number of patients with outpatient confirmation of Dementia or MCI

  30 days

Study Arms (1)

ED delirium & dementia screening & outpatient referral

Routine ED screening for delirium and memory problems with referral for outpatient assessment of cognitive impairment.

Diagnostic Test: PD4ED 3-step intervention (ED assessment, outpatient assessment, Brain health plan)

Interventions

PD4ED 3-step intervention (ED assessment, outpatient assessment, Brain health plan) DIAGNOSTIC_TEST

1. ED assessment for suspected dementia. 2. positive ED patients referred for outpatient clinic cognitive impairment assessment. 3. positive clinic patients referred to primary care with brain health patient plan.

ED delirium & dementia screening & outpatient referral

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

All community dwelling ED patients 65 years of age or older seen in the Yale New Haven Health System (YNHHS) St. Raphael's Campus (SRC) ED or Northwestern Memorial Hospital (NMH) ED.

You may qualify if:

• Adults age 65 or older
• Discharged from the adult ED at YNHH or the ED at NMH

You may not qualify if:

• Documented or known history of dementia
• Alcohol/substance intoxication while in the ED
• Non-English or Non-Spanish speaking

Sponsors & Collaborators

• Yale University: lead
• National Institute on Aging (NIA): collaborator

Study Sites (2)

Yale New Haven Hospital

New Haven, Connecticut, 06512, United States

Location

Northwestern

Chicago, Illinois, 60611, United States

Location

MeSH Terms

Conditions

Cognitive Dysfunction; Dementia; Delirium

Condition Hierarchy (Ancestors)

Cognition Disorders; Neurocognitive Disorders; Mental Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Confusion; Neurobehavioral Manifestations; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Results Point of Contact

• Title: Ula Hwang, MD
• Organization: Yale University

ula.hwang@yale.edu

+1 (203) 7371774

Study Officials

• Ula Hwang, MD

  Yale University

  PRINCIPAL INVESTIGATOR

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: March 25, 2021
• First Posted: April 15, 2021
• Study Start: March 1, 2021
• Primary Completion: August 15, 2022
• Study Completion: August 15, 2022
• Last Updated: March 7, 2024
• Results First Posted: October 23, 2023

Record last verified: 2024-02

Locations

US (2)