Anderson Study 1 - Tart Cherry Study
AS1
Effects Of Tary Cherry Ingestion On Food-Induced Serum Uric Acid Elevation
1 other identifier
interventional
24
1 country
1
Brief Summary
The purpose of this study is to examine if tart cherry reduces food-induced elevations in serum uric acid.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at below P25 for not_applicable
Started Apr 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
April 10, 2020
CompletedFirst Submitted
Initial submission to the registry
March 31, 2021
CompletedFirst Posted
Study publicly available on registry
April 8, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 1, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2021
CompletedJune 27, 2024
October 1, 2022
1.1 years
March 31, 2021
June 25, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
Uric Acid Changes
Serum Uric Acid changes to ingesting a high purine containing meal,
Measured at baseline (prior to supplementation (Pre)), and after 60, 120, 180 and 240 minutes
Secondary Outcomes (2)
Side Effects Assessment
Measured at baseline prior to supplementation (Pre)
Side Effects Assessment
Measured after 240 minutes (Post)
Study Arms (2)
Placebo
PLACEBO COMPARATORDextrose (480 mg)
Active
EXPERIMENTALTart Cherry (480 mg)
Interventions
Eligibility Criteria
You may qualify if:
- They are healthy males or females ages 30 to 60 years with fasting serum uric acid (UA) levels between 5.5 and 8.0 mg/dl obtained during the familiarization/screening visit;
- They have a willingness to provide voluntary, written, informed consent to participate in the study;
You may not qualify if:
- They take prescription (Rx) medications (i.e., Uloric, Krystexxa, etc.) or dietary supplements known to have UA-reducing activity (i.e., black cherry, devil's claw, grape seed extracts, etc.);
- They have regular diseases requiring regular prescription (Rx) medications (birth control is allowed);
- They have abnormal/out of range values in laboratory tests determined at the familiarization/screening visit;
- They have an allergy to tart cherry or immunoglobulin E;
- They are pregnant, trying to become pregnant or breastfeeding;
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Texas A&M Universitylead
- Anderson Global Group, LLCcollaborator
Study Sites (1)
Exercise & Sport Nutrition Lab - Human Clinical Research Facility
College Station, Texas, 77845, United States
Related Publications (1)
Gonzalez DE, Kendra JA, Dickerson BL, Yoo C, Ko J, McAngus K, Martinez V, Leonard M, Johnson SE, Xing D, Sowinski RJ, Rasmussen CJ, Kreider RB. Effects of Acute and One-Week Supplementation with Montmorency Tart Cherry Powder on Food-Induced Uremic Response and Markers of Health: A Proof-of-Concept Study. Nutrients. 2024 Oct 6;16(19):3391. doi: 10.3390/nu16193391.
PMID: 39408358DERIVED
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Richard B Kreider, PhD
Texas A&M University
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- DOUBLE
- Who Masked
- PARTICIPANT, INVESTIGATOR
- Masking Details
- Double (Participant, Investigator)
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Executive Director, Human Clinical Research Facility
Study Record Dates
First Submitted
March 31, 2021
First Posted
April 8, 2021
Study Start
April 10, 2020
Primary Completion
June 1, 2021
Study Completion
June 1, 2021
Last Updated
June 27, 2024
Record last verified: 2022-10
Data Sharing
- IPD Sharing
- Will not share