Frequency of Pes Planus and Posterior Tibial Tendon Dysfunction in Patients With Ankylosing Spondylitis

NCT04810715 | Completed

• 1 other identifier: NEAS2021
• Study Type: observational
• Target: 100
• Locations: 1 country
• Sites: 1

Brief Summary

This investigation aims to investigate the frequency of pes planus and posterior tibial tendon dysfunction in patients with ankylosing spondylitis.

Conditions

Posterior Tibial Tendon Dysfunction; Pes Planus; Spondylitis, Ankylosing

Keywords

Posterior Tibial Tendon Dysfunction; Ultrasonographic Evaluation; Pes Planus

Outcome Measures

Primary Outcomes (3)

• Bath Ankylosing Spondylitis Disease Activity Index (BASDAI)

  BASDAI includes six questions evaluating five important findings of the disease (Fatigue, hip and spine pain, swelling and pain in peripheral joints, enthesitis, duration and severity of morning stiffness). The pain levels of the patients will be evaluated with a Visual Analog scale (0: I have no pain, 10: I have very severe pain). Higher scores mean active disease.

  Will be done only once on the first day after inclusion

• Bath Ankylosing Spondylitis Functional Index (BASFI)

  BASFI; consists of eight questions that evaluate the function of patients with AS and two questions that evaluate their daily life. Higher scores indicate greater limitations.

  Will be done only once on the first day after inclusion

• Ankylosing Spondylitis Quality of Life Scale (ASQOL)

  Ankylosing Spondylitis Quality of Life (ASQoL) scale is a disease-specific assessment parameter designed to measure health-related quality of life. It includes yes or no questions with a total score ranging from 0 to 18. The lower scores represent better quality of life.

  Will be done only once on the first day after inclusion

Secondary Outcomes (6)

• Functional reach test

  Will be done only once on the first day after inclusion

• Timed up and go test (TUG)

  Will be done only once on the first day after inclusion

• Berg Balance Scale

  Will be done only once on the first day after inclusion

• Foot and Ankle Outcome Score (FAOS)

  Will be done only once on the first day after inclusion

• Ultrasonographic evaluation of the posterior tibial tendon

  Will be done only once on the first day after inclusion

Study Arms (1)

Patient Group

Anklyosing Spondilitis

Other: Patients with Ankylosing Spondylitis

Interventions

Patients with Ankylosing Spondylitis OTHER

Observational study, not applicable

Patient Group

Eligibility Criteria

• Age: 20 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Outpatient clinic patients

You may qualify if:

• Participitans who apply to the rheumatology outpatient clinic between the ages of 20-70 and who have been diagnosed with ankylosing spondylitis according to the Modified Newyork criteria will be included in this study.
• Ankylosing Spondilitis

You may not qualify if:

• Malignity
• Previous ankle surgery history
• Muscle disease
• Neuropsychiatric illnesses
• İmbalance
• Visual problems
• Deafness

Sponsors & Collaborators

• Afyonkarahisar Health Sciences University: lead

Study Sites (1)

Afyonkarahisar

Afyonkarahisar, 0300, Turkey (Türkiye)

Location

Related Publications (3)

• Arnoldner MA, Gruber M, Syre S, Kristen KH, Trnka HJ, Kainberger F, Bodner G. Imaging of posterior tibial tendon dysfunction--Comparison of high-resolution ultrasound and 3T MRI. Eur J Radiol. 2015 Sep;84(9):1777-81. doi: 10.1016/j.ejrad.2015.05.021. Epub 2015 May 21.

  PMID: 26037267 BACKGROUND

• Guelfi M, Pantalone A, Mirapeix RM, Vanni D, Usuelli FG, Guelfi M, Salini V. Anatomy, pathophysiology and classification of posterior tibial tendon dysfunction. Eur Rev Med Pharmacol Sci. 2017 Jan;21(1):13-19.

  PMID: 28121362 BACKGROUND

• Hasler P, Hintermann B, Meier M. Posterior tibial tendon dysfunction and MR imaging in rheumatoid arthritis. Rheumatol Int. 2002 May;22(1):38-40. doi: 10.1007/s00296-002-0183-1.

  PMID: 12120910 BACKGROUND

MeSH Terms

Conditions

Posterior Tibial Tendon Dysfunction; Flatfoot; Spondylitis, Ankylosing

Interventions

HLA-B Antigens

Condition Hierarchy (Ancestors)

Foot Diseases; Musculoskeletal Diseases; Talipes; Foot Deformities, Acquired; Foot Deformities; Foot Deformities, Congenital; Lower Extremity Deformities, Congenital; Limb Deformities, Congenital; Musculoskeletal Abnormalities; Congenital Abnormalities; Congenital, Hereditary, and Neonatal Diseases and Abnormalities; Axial Spondyloarthritis; Spondylarthropathies; Spondylarthritis; Spondylitis; Spinal Diseases; Bone Diseases; Ankylosis; Joint Diseases; Arthritis

Intervention Hierarchy (Ancestors)

Histocompatibility Antigens Class I; Membrane Glycoproteins; Glycoproteins; Glycoconjugates; Carbohydrates; Proteins; Amino Acids, Peptides, and Proteins; Membrane Proteins; Histocompatibility Antigens; Antigens, Surface; Antigens; Biological Factors; HLA Antigens; Isoantigens

Study Officials

• Nuran EYVAZ, MD

  Afyonkarahisar Health Sciences University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor

Study Record Dates

• First Submitted: March 19, 2021
• First Posted: March 23, 2021
• Study Start: March 1, 2021
• Primary Completion: September 1, 2022
• Study Completion: September 1, 2022
• Last Updated: September 28, 2022

Record last verified: 2022-09

Locations

TU (1)