NCT04788225

Brief Summary

Approximately 85% of ankle injuries are lateral region injuries.Surgical repair of lateral ligaments is indicated if there is more than 20 degrees of varus or more than 15 mm translation, if conservative treatment is ineffective and degree of damage is high and chronic instability has developed.After the surgery in addition to pain and edema control, weight transfer is not performed on the ankle for 6 weeks.Therefore, this process may adversely affect the muscle strength and range of motion of the ankle, and lower extremity performance and muscular synergies of balance.Although pathological changes caused by ligament damage have been investigated very well in the literature, it is not clear how surgical repair affects these changes. In our study we aim to investigate post-surgical changes. Primary aim of the study is to evaluate the balance parameters of individuals who have undergone anterior talofibular ligament and / or calcaneofibular ligament repair, and its secondary purpose is to evaluate lower extremity performance, ankle functionality, pain, range of motion and muscle strength and compare them with healthy individuals. Our hypothesis is that the balance, lower extremity performance and functionality, pain, range of motion and muscle strength of patients who have undergone ankle lateral ligament repair are worse than healthy individuals.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Feb 2021

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 12, 2021

Completed
15 days until next milestone

First Submitted

Initial submission to the registry

February 27, 2021

Completed
10 days until next milestone

First Posted

Study publicly available on registry

March 9, 2021

Completed
11 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 1, 2022

Completed
Last Updated

March 9, 2021

Status Verified

March 1, 2021

Enrollment Period

12 months

First QC Date

February 27, 2021

Last Update Submit

March 4, 2021

Conditions

Keywords

Lateral ankle ligaments repairPostural BalancePhysical Functional Performance

Outcome Measures

Primary Outcomes (4)

  • Static balance assessment-Postural Stability Test

    Postural Stability will be measured with the Biodex-BioSway 950-462 static balance device in single foot stance and double foot stance.

    1 year postoperatively

  • Static balance assessment-Stability Limit Test

    Stability Limit will be measured with the Biodex-BioSway 950-462 static balance device in double foot stance.

    1 year postoperatively

  • Static balance assessment-Modified Sensori Organization Test

    Modified Sensori Organization will be measured with the Biodex-BioSway 950-462 static balance device in double foot stance.

    1 year postoperatively

  • Dynamic balance assessment

    Dynamic balances will be evaluated with the Y balance test.

    1 year postoperatively

Secondary Outcomes (5)

  • Jumping performance assessment

    1 year postoperatively

  • Walking ability

    1 year postoperatively

  • Lower limb functionality assessment

    1 year postoperatively

  • Foot and ankle functionality assessment

    1 year postoperatively

  • ROM assessment

    1 year postoperatively

Study Arms (2)

Patients with ATFL repair by arthroscopic method

Patients who have passed at least 1 year after the operation Unilateral arthroscopic ATFL repair Between the ages of 18-65 Volunteer to participate in the study Without any orthopedic conditions, neuromuscular disease, balance disorder, cognitive disorder No history of fracture and surgical operation of the lower extremity

Other: Balance assessmentOther: Functionality assessmentOther: Performance assessmentOther: ROM assessment

Control group

Between the ages of 18-65 Volunteer to participate in the study Healthy individuals with no disease

Other: Balance assessmentOther: Functionality assessmentOther: Performance assessmentOther: ROM assessment

Interventions

Static balances will be measured with the Biodex-BioSway 950-462 static balance device according to 3 different standard test procedures (Postural Stability Test, Stability Limit Test and Modified Sensori Organization Test) in single foot stance and double foot stance. Dynamic balances will be evaluated with the Y balance test.

Also known as: Clinical assessment
Control groupPatients with ATFL repair by arthroscopic method

Functionality will be evaluated with the Lower Extremity Functional Scale and AOFAS (American Orthopedic Foot and Ankle Society Ankle-Hindfoot Scale)

Also known as: Clinical assessment
Control groupPatients with ATFL repair by arthroscopic method

Performance evaluation will be made with a single leg jump test and time up and go test.

Also known as: Clinical assessment
Control groupPatients with ATFL repair by arthroscopic method

Range of motion (ROM) of the ankle will be measured with an electrogonyometer in dorsi-plantar flexion.

Also known as: Clinical assessment
Control groupPatients with ATFL repair by arthroscopic method

Eligibility Criteria

Age18 Years - 65 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who have undergone ATFL repair surgery at Gazi University Hospital The healthy control group will consist of patient relatives or volunteers to participate in the study.

You may qualify if:

  • Patients who have passed at least 1 year after the operation Unilateral arthroscopic ATFL repair Volunteer to participate in the study

You may not qualify if:

  • Any orthopedic conditions, neuromuscular disease, balance disorder, cognitive disorder, history of fracture and surgical operation of the lower extremity

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Inci Ayas

Ankara, 06560, Turkey (Türkiye)

RECRUITING

Study Officials

  • seyit çıtaker

    Gazi University

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

February 27, 2021

First Posted

March 9, 2021

Study Start

February 12, 2021

Primary Completion

February 1, 2022

Study Completion

February 1, 2022

Last Updated

March 9, 2021

Record last verified: 2021-03

Locations