Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department

NCT04779099 | Completed DMC

• 1 other identifier: 2020-796
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour. There is no established evidence-based brief intervention for patients with BPD in ED settings, however a 4-session psychotherapeutic intervention for people with personality disorders in ED settings was tested in Australia and showed promising results in reduced health care utilization. The proposed pilot randomized controlled trial will assess the feasibility of delivering this 4-session intervention in the ED for people with BPD who present with suicidal ideation or self-harm with the aim of reducing health care utilization.

Conditions

Borderline Personality Disorder; Suicide and Self-harm

Outcome Measures

Primary Outcomes (1)

• Primary clinical outcome measure - Emergency Department Visits

  The primary clinical outcome will be the mean group difference in frequency of ER visits on the Client Service Receipt Inventory (CSRI)

  1, 3 and 6 month follow up

Study Arms (2)

4-session intervention

EXPERIMENTAL

Behavioral: Brief 4-session intervention for borderline personality disorder; Behavioral: Treatment as usual

Treatment as usual

ACTIVE COMPARATOR

Behavioral: Treatment as usual

Interventions

Brief 4-session intervention for borderline personality disorder BEHAVIORAL

Intervention consists of weekly 50-minute 1:1 sessions focused on psycho-education, here-and-now problem solving and safety planning. One of the sessions can involve a significant other to provide psychoeducation about the disorder and to facilitate support. This intervention is detailed in a published manual.

4-session intervention

Treatment as usual BEHAVIORAL

TAU comprises access to psychiatric assessment, medication review, and unscheduled sessions with allied health professionals using a drop-in model of care.

4-session intervention; Treatment as usual

Eligibility Criteria

• Age: 16 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• aged 16 or older
• presenting to ED with self-harm and/or suicidal ideation; and
• meeting criteria for BPD on the Structured Clinical Interview for DSM-5 Personality Disorders

You may not qualify if:

• unable to give informed consent;
• meeting DSM-5 criteria for severe substance use disorder, schizophrenia spectrum disorder or bipolar disorder I mania based on the Structured Clinical Interview for DSM-5 (28); and/or
• IQ \< 70 based on the Wechsler Test of Adult Reading

Sponsors & Collaborators

• Centre for Addiction and Mental Health: lead

Study Sites (1)

Centre for Addiction and Mental Health

Toronto, Ontario, M6J1H4, Canada

Location

MeSH Terms

Conditions

Borderline Personality Disorder; Suicide; Self-Injurious Behavior

Interventions

Therapeutics

Condition Hierarchy (Ancestors)

Personality Disorders; Mental Disorders; Behavioral Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: INVESTIGATOR, OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Psychiatrist and Clinician Scientist

Study Record Dates

• First Submitted: March 1, 2021
• First Posted: March 3, 2021
• Study Start: October 22, 2021
• Primary Completion: May 24, 2023
• Study Completion: May 24, 2023
• Last Updated: December 4, 2024

Record last verified: 2024-12

Locations

CA (1)