NCT04772417

Brief Summary

The 1-minute sit-to-stand test (1MSTS) is a widely used functional capacity test and has promising predictive potential. Current standards of practice suggest the use of a chair with a standardized height. However, this practice makes the test more demanding for taller individuals than for shorter individuals. This implies over- or underestimation of functional capacity depending on body morphology. Therefore, the aim of this study is to investigate the influence of knee joint angle, femur length and bodyweight on the 1MSTS performance in healthy subjects with different morphology.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
30

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Apr 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

February 21, 2021

Completed
5 days until next milestone

First Posted

Study publicly available on registry

February 26, 2021

Completed
2 months until next milestone

Study Start

First participant enrolled

April 20, 2021

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 3, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 3, 2022

Completed
Last Updated

November 8, 2022

Status Verified

November 1, 2022

Enrollment Period

1.5 years

First QC Date

February 21, 2021

Last Update Submit

November 6, 2022

Conditions

Outcome Measures

Primary Outcomes (1)

  • Repetitions in the 1-minute sit-to-stand test

    Comparison between the procedures

    Day 1

Secondary Outcomes (1)

  • Predictors towards performance in the 1-minute sit-to-stand test

    Day 1

Interventions

The individuals perform two tests from a standardized chair (seat height 46cm).

The individuals perform two tests from an individualized chair (seat height adjusted so that the starting position elicits a knee flexion angle of 90°).

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Healthy individuals

You may qualify if:

  • Informed consent as documented by signature
  • Age 18 and older
  • Healthy
  • Ability to conduct a 1-minute sit-to-stand-test
  • Ability to follow study procedures and instructions in German

You may not qualify if:

  • Known cardiopulmonary or metabolic diseases (e.g., heart disease, diabetes mellitus etc.)
  • Physical or intellectual impairment precluding informed consent or protocol adherence
  • Respiratory infection in the last two weeks
  • Pain during sit-to-stand movement

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospital Zurich

Zurich, 8091, Switzerland

Location

Related Publications (1)

  • Kuhn M, Vollenweider S, Clarenbach CF, Kohlbrenner D. The effects of standardised versus individualised seat height on 1-minute sit-to-stand test performance in healthy individuals: a randomised crossover trial. Eur J Appl Physiol. 2023 Jul;123(7):1543-1551. doi: 10.1007/s00421-023-05174-8. Epub 2023 Mar 17.

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

February 21, 2021

First Posted

February 26, 2021

Study Start

April 20, 2021

Primary Completion

November 3, 2022

Study Completion

November 3, 2022

Last Updated

November 8, 2022

Record last verified: 2022-11

Locations