Performance Indicators of the SARC-F Questionnaire in Acute Care

NCT04757454 | Completed

• 1 other identifier: CHUB SARC-F
• Study Type: observational
• Target: 105
• Locations: 1 country
• Sites: 1

Brief Summary

The study applies the Sluggishness, Assistance in walking, Rising from a chair, Climb stairs, Falls (SARC-F) questionnaire in older patients hospitalized in an acute care geriatric unit and aims to determine its performance indicators to screen for sarcopenia according to the revised European Consensus on definition and diagnosis (EWGSOP2) within this population

Conditions

Sarcopenia; Sensitivity; Old Age; Debility

Outcome Measures

Primary Outcomes (3)

• Sensitivity of the SARC-F questionnaire as screening method compared to the gold standard, which is the revised European consensus on definition and diagnosis

  Sensitivity, measured as a percentage (%)

  September 2019-November 2020

• Specificity of the SARC-F questionnaire as a screening method, compared to the gold standard which is the revised European Consensus on definition and diagnosis of sarcopenia (EWGSOP2)

  Specificity, measured as a percentage (%)

  September 2019-November 2020

• Overall concordance agreement between the SARC-F questionnaire as a screening method and the gold standard method, which is the EWGSOP2

  Cohen-kappa coefficient, measured as a percentage (%)

  September 2019-November 2020

Secondary Outcomes (1)

• Health adverse outcomes based on the screening and diagnosis of sarcopenia as recommended by the EWGSOP2

  1-year follow-up

Interventions

5-item SARC-F questionnaire DIAGNOSTIC_TEST

Administration of the 5-item SARC-F questionnaire in patients admitted to an acute care unit

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients aged 65 and over hospitalized in an acute care geriatric unit due to acute medical conditions, where the SARC-F questionnaire and the EWGSOP2 was available

You may qualify if:

• Patients aged 65 and over
• Hospitalized in an acute care geriatric unit due to acute health issues or acute medical conditions
• With SARC-F, hand-grip strength and dual-energy X-ray absorptiometry administered during hospital admission

You may not qualify if:

• SARC-F unavailable
• Unwilling to collaborate in the sarcopenia assessment
• Unwilling to sign the informed consent

Sponsors & Collaborators

• Brugmann University Hospital: lead

Study Sites (1)

Brugmann university hospital

Brussels, 1020, Belgium

Location

Related Publications (4)

• Sanchez-Rodriguez D, Marco E, Davalos-Yerovi V, Lopez-Escobar J, Messaggi-Sartor M, Barrera C, Ronquillo-Moreno N, Vazquez-Ibar O, Calle A, Inzitari M, Piotrowicz K, Duran X, Escalada F, Muniesa JM, Duarte E. Translation and Validation of the Spanish Version of the SARC-F Questionnaire to Assess Sarcopenia in Older People. J Nutr Health Aging. 2019;23(6):518-524. doi: 10.1007/s12603-019-1204-z.

  PMID: 31233072 BACKGROUND

• Piotrowicz K, Gluszewska A, Czesak J, Fedyk-Lukasik M, Klimek E, Sanchez-Rodriguez D, Skalska A, Gryglewska B, Grodzicki T, Gasowski J. SARC-F as a case-finding tool for sarcopenia according to the EWGSOP2. National validation and comparison with other diagnostic standards. Aging Clin Exp Res. 2021 Jul;33(7):1821-1829. doi: 10.1007/s40520-020-01782-y. Epub 2021 Jan 28.

  PMID: 33506313 BACKGROUND

• Sanchez-Rodriguez D, Marco E, Cruz-Jentoft AJ. Defining sarcopenia: some caveats and challenges. Curr Opin Clin Nutr Metab Care. 2020 Mar;23(2):127-132. doi: 10.1097/MCO.0000000000000621.

  PMID: 31789867 BACKGROUND

• Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyere O, Cederholm T, Cooper C, Landi F, Rolland Y, Sayer AA, Schneider SM, Sieber CC, Topinkova E, Vandewoude M, Visser M, Zamboni M; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019 Jan 1;48(1):16-31. doi: 10.1093/ageing/afy169.

  PMID: 30312372 BACKGROUND

MeSH Terms

Conditions

Sarcopenia; Hypersensitivity; Frailty

Condition Hierarchy (Ancestors)

Muscular Atrophy; Neuromuscular Manifestations; Neurologic Manifestations; Nervous System Diseases; Atrophy; Pathological Conditions, Anatomical; Pathological Conditions, Signs and Symptoms; Signs and Symptoms; Immune System Diseases; Pathologic Processes

Study Officials

• Murielle Surquin

  Head of the Geriatrics Department

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Head of the Internal Medicine and Geriatrics Department

Study Record Dates

• First Submitted: February 8, 2021
• First Posted: February 17, 2021
• Study Start: September 1, 2019
• Primary Completion: November 11, 2020
• Study Completion: November 11, 2020
• Last Updated: February 17, 2021

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share

Locations

BE (1)