Mortality Due to COVID-19 in the COVID-AGEBRU Study

NCT04756479 | Completed

• 1 other identifier: COVID-19 AGE-BRUGMANN 2020/111
• Study Type: observational
• Target: 160
• Locations: 1 country
• Sites: 1

Brief Summary

The COVID-Age Brugmann study aims to identify the clinical predictors of mortality risk in older patients admitted to an acute care unit due to COVID-19

Conditions

Covid19; Old Age; Debility; Morbidity, Multiple

Outcome Measures

Primary Outcomes (1)

• All-cause mortality during hospital admission (admission up to discharge time)

  Vital status was obtained from medical records

  Through study completion, an average of one month.

Secondary Outcomes (1)

• Prevalence of medical diseases and geriatric syndromes

  Through study completion, an average of one month.

Eligibility Criteria

• Age: 70 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Consecutive patients aged 70 and over hospitalized in an acute care unit in Brugmann university hospital, in Belgium, due to COVID-19 in the period Mars to June 2020.

You may qualify if:

• Patients aged 70 and older
• Patients admitted to an acute care geriatric unit due to COVID-19
• Patients with COVID-19 by PCR, serology or CT scan suggestive of this disease

Sponsors & Collaborators

• Brugmann University Hospital: lead

Study Sites (1)

CHU Brugmann

Brussels, 1020, Belgium

Location

Related Publications (3)

• Mendes A, Serratrice C, Herrmann FR, Genton L, Perivier S, Scheffler M, Fassier T, Huber P, Jacques MC, Prendki V, Roux X, Di Silvestro K, Trombert V, Harbarth S, Gold G, Graf CE, Zekry D. Predictors of In-Hospital Mortality in Older Patients With COVID-19: The COVIDAge Study. J Am Med Dir Assoc. 2020 Nov;21(11):1546-1554.e3. doi: 10.1016/j.jamda.2020.09.014. Epub 2020 Sep 15.

  PMID: 33138936 BACKGROUND

• Menager P, Briere O, Gautier J, Riou J, Sacco G, Brangier A, Annweiler C, Geria-Covid Study Group OBOT. Regular Use of VKA Prior to COVID-19 Associated with Lower 7-Day Survival in Hospitalized Frail Elderly COVID-19 Patients: The GERIA-COVID Cohort Study. Nutrients. 2020 Dec 24;13(1):39. doi: 10.3390/nu13010039.

  PMID: 33374341 BACKGROUND

• Miralles O, Sanchez-Rodriguez D, Marco E, Annweiler C, Baztan A, Betancor E, Cambra A, Cesari M, Fontecha BJ, Gasowski J, Gillain S, Hope S, Phillips K, Piotrowicz K, Piro N, Sacco G, Saporiti E, Surquin M, Vall-Llosera E. Unmet needs, health policies, and actions during the COVID-19 pandemic: a report from six European countries. Eur Geriatr Med. 2021 Feb;12(1):193-204. doi: 10.1007/s41999-020-00415-x. Epub 2020 Oct 15.

  PMID: 33057981 BACKGROUND

MeSH Terms

Conditions

COVID-19; Frailty

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Murielle MS Surquin, MD PhD

  CHU Brugmann, Director of the Geriatrics Department

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Geriatrics Department

Study Record Dates

• First Submitted: February 8, 2021
• First Posted: February 16, 2021
• Study Start: March 1, 2020
• Primary Completion: June 30, 2020
• Study Completion: June 30, 2020
• Last Updated: April 6, 2022

Record last verified: 2022-03

Locations

BE (1)