Effects of High-intensity Aerobic Training on Balance, Walking Capacity, and Quality of Life in Patients With Sub-acute Stroke.

NCT04752124 | Completed

• 1 other identifier: 555
• Study Type: interventional
• Target: 50
• Locations: 1 country
• Sites: 1

Brief Summary

Stroke is one of the major cause of morbidity and mortality and the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important impact on patient's quality of life and which increase the costs for health and social services. After stroke, impairments in ADLs and functional status, deterioration in health related quality of life can be seen. The purpose of this study is to Determine the effect of high intensity speed based treadmill training on Balance, Walking capacity and quality of life in sub-acute stroke.

Conditions

Stroke

Keywords

Cerebrovascular accident; Aerobic exercise; High intensity interval training

Outcome Measures

Primary Outcomes (1)

• 6 minute walk test

  To determine the endurance after stroke

  6 weeks of training

Secondary Outcomes (2)

• Berg Balance scale

  5 weeks

• Stroke Impact scale

  5 weeks

Study Arms (2)

HIIT+CT

ACTIVE COMPARATOR

HIIT combined with conventional rehabilitation.

Other: Exercise Therapy; Other: conventional therapy

Conventional therapy

PLACEBO COMPARATOR

Conventional rehabilitation will be provided to this group of patients.

Other: conventional therapy

Interventions

Exercise Therapy OTHER

High intensity speed based interval treadmill training

HIIT+CT

conventional therapy OTHER

conventional physical therapy

Conventional therapy; HIIT+CT

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• age 40-80 years; first episode of stroke; \>4 weeks of stroke onset; hemiparesis resulting from unilateral ischaemic stroke; Ashworth score of 0 or 1, indicating no spasticity or slight spasticity over the affected lower limb, respectively; mini-mental state examination score ≥23; ability to perform independent walking for at least five minutes with or without an assistive device (FAC=3). All patients will be determined to be in stable cardiovascular condition with a low although slightly greater risk for vigorous exercise than for apparently healthy persons (class B according to the American College of Sports Medicine \[ACSM\]).13

You may not qualify if:

• Participants will be excluded from the study if they had any of the following: (1) chronic cardiorespiratory or metabolic diseases; (2) severe osteoporosis; and (3) lesions pertaining to the brainstem or cerebellum; (4) having resting blood pressure above 160/100 mmHg even after taking medications; (5) cardiovascular comorbidity (aortic stenosis, depression of ST-segment, heart failure, arrhythmias, unstable angina, hypertrophic cardio-myopathy); (6) transient ischemic attack; (7) by-pass surgery in the recent three months; and (8) other musculoskeletal problems that prevented the participants from doing aerobic activity.

Sponsors & Collaborators

• Government College University Faisalabad: lead

Study Sites (1)

Bin Inam Rehabilitation Center.

Faisalābad, Punjab Province, 46000, Pakistan

Location

Related Publications (1)

• Lau KW, Mak MK. Speed-dependent treadmill training is effective to improve gait and balance performance in patients with sub-acute stroke. J Rehabil Med. 2011 Jul;43(8):709-13. doi: 10.2340/16501977-0838.

  PMID: 21698340 RESULT

MeSH Terms

Conditions

Stroke

Interventions

Exercise Therapy

Condition Hierarchy (Ancestors)

Cerebrovascular Disorders; Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Vascular Diseases; Cardiovascular Diseases

Intervention Hierarchy (Ancestors)

Rehabilitation; Aftercare; Continuity of Patient Care; Patient Care; Therapeutics; Physical Therapy Modalities

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Physiotherapist

Study Record Dates

• First Submitted: February 9, 2021
• First Posted: February 12, 2021
• Study Start: November 7, 2020
• Primary Completion: February 27, 2021
• Study Completion: March 15, 2021
• Last Updated: March 16, 2021

Record last verified: 2021-03

Locations

PA (1)