Chinese Nutritional Risk Screening and Intervention Registration Study in Geriatric Patients

NCT04751032 | Completed DMC

• 1 other identifier: NCT2020090120210601
• Study Type: observational
• Target: 2,000
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a multi-center observational study, led by the Department of Geriatrics, Peking Union Medical College Hospital, with 99 tertiary hospitals as sub-centers. Patients in the geriatrics department from September 2020 to September 2021 are consecutively enrolled .Basic information and nutritional risk assessment is registered and the outcome within 90 days after hospitalization will be recorded.Daily energy, protein and fiber are 75% of the target amount as the standard for feeding.

Conditions

Malnutrition; Old Age

Keywords

malnutrition; older adults; adverse outcomes; nutrition intervention

Outcome Measures

Primary Outcomes (4)

• Rate of mortality

  all cause mortality

  within 90 days after hospitalization

• Number of Participants with respiratory, urinary or gastrointestinal infections diagnosed by clinicians

  Any infection diagnosed by a formal medical institution.Infections that require a doctor's prescription of antibiotics indicated in the medical records or diagnosis reports provided by the participants, including the respiratory tract, urinary tract, gastrointestinal tract, etc.The report or diagnosis certificate has relevant evidence, for example, the test indicates that the white blood cell is increased or the high-sensitivity C-reactive protein is increased.

  within 90 days after hospitalization

• Number of Participants with unplanned hospitalization for acute illness

  Visits reported by participants because of an acute illness rather than regular visits.Hospital stays longer than 48 hours will be counted, but outpatient visits will not be counted.

  within 90 days after hospitalization

• Number of Participants with fall

  Any falls reported by the participants within 90 days will be recorded. The cause of the fall and whether it is accompanied by a fracture shall be recorded.

  within 90 days after hospitalization

Secondary Outcomes (3)

• Number of Participants with the albumin changes

  Within 90 days after hospitalization

• Number of Participants with the physical function changes assessed by katz activity of the daily living（ADL）

  Within 90 days after hospitalization

• Number of Participants with the quality of the life changes according to the EuroQol Five Dimensions Questionnaire（EQ-5D）

  Within 90 days after hospitalization

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients in the geriatrics/geriatrics department of tertiary hospitals from September 2020 to September 2021 are consecutively enrolled.

You may qualify if:

• Patients aged ≥65 years old in geriatrics;
• Expected hospitalization ≥4 days;
• Patients with NRS 2002≥3 points;
• Sign informed notice.

You may not qualify if:

• End-stage patients (estimated survival time ≤ 3 months);
• Transfer to other departments during hospitalization;
• Contraindications to nutritional therapy (such as hemodynamic instability);
• Have participated in other nutritional research projects.

Sponsors & Collaborators

• Chinese Medical Association: lead

Study Sites (1)

Department of Geriatrics,Peking Union Medical College Hospital

Beijing, Beijing Municipality, 100730, China

Location

Related Publications (1)

• Li M, Jiang S, Li J, Chen X, Ma L, Guo Q, Wang Y, Luo L, An L, Wu Y, Huang W, Yuan L, Wang L, Ding X, Zhao X, Zhang Z, Zhang H, Wu Y, Yang R, Liu Y, Cao J, Liu X. Effectiveness and safety of oral nutrition in older patients with moderate dysphagia: a real-world cohort study in geriatric inpatients. BMC Geriatr. 2025 Jul 31;25(1):571. doi: 10.1186/s12877-025-06175-2.

  PMID: 40745263 DERIVED

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition Disorders; Nutritional and Metabolic Diseases

Study Officials

• Xiaohong Liu, MD &PHD

  Department of Geriatrics,Peking Union Medical College Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 3 Months
• Sponsor Type: NETWORK
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 23, 2021
• First Posted: February 11, 2021
• Study Start: September 1, 2020
• Primary Completion: December 31, 2021
• Study Completion: December 31, 2021
• Last Updated: May 4, 2025

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share

Locations

CN (1)