NCT04703881

Brief Summary

To evaluate tolerance and acceptability of 'AYMES ActaGain' in patients requiring supplementary oral nutritional support compared with currently available alternatives.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
17

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Jul 2020

Shorter than P25 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2020

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2020

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

January 5, 2021

Completed
6 days until next milestone

First Posted

Study publicly available on registry

January 11, 2021

Completed
Last Updated

January 11, 2021

Status Verified

January 1, 2021

Enrollment Period

3 months

First QC Date

January 5, 2021

Last Update Submit

January 7, 2021

Conditions

Outcome Measures

Primary Outcomes (1)

  • Gastro-Intestinal Tolerance when consuming AYMES ActaGain

    To assess gastro-intestinal tolerance of 'AYMES ActaGain' in patients in the community requiring oral nutritional supplementation. Monitoring includes recording the number of any GI complaints via a daily diary.

    30 days

Secondary Outcomes (2)

  • Acceptability and Palatability of Consuming the Nutritional Supplement: questionnaire

    30 days

  • Compliance

    30 days

Study Arms (1)

AYMES ActaGain

EXPERIMENTAL

Patients of the intended target group (e.g. MUST score ≥ 1, with or at risk of disease related malnutrition) with an anticipated period of nutritional support ≥ 4 weeks will be changed / started on an equivalent prescription of 'AYMES ActaGain' for a period of 30 days.

Dietary Supplement: AYMES ActaGain

Interventions

AYMES ActaGainDIETARY_SUPPLEMENT

AYMES ActaGain is a Food for Special Medical Purposes (FSMP) and must, therefore, be used under medical supervision. It is designed as a supplement to the diet but can also be used as a sole source of nutrition.

AYMES ActaGain

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male and female patients.
  • ≥ 18 years of age.
  • Patients of the intended target group (e.g. MUST score ≥ 1, with or at risk of disease related malnutrition) with an anticipated period of nutritional support ≥ 4 weeks.
  • Patient is able and willing to provide written informed consent.

You may not qualify if:

  • Patients with medical or dietary contraindication to any feed ingredients.
  • Patients requiring sole enteral tube feeding or parenteral nutrition.
  • Patients with chronic renal disease requiring dialysis.
  • Patients with liver failure.
  • Patients for whom the investigator has concerns regarding the ability or willingness of the patient and or carer to comply with protocol requirements.
  • Patients assessed by a Speech and Language Therapist who require thickened fluids.
  • Participation in any other studies that may interfere with this study.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AYMES International Ltd.

Haywards Heath, RH16 9PL, United Kingdom

Location

MeSH Terms

Conditions

Malnutrition

Condition Hierarchy (Ancestors)

Nutrition DisordersNutritional and Metabolic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 5, 2021

First Posted

January 11, 2021

Study Start

July 1, 2020

Primary Completion

October 1, 2020

Study Completion

October 1, 2020

Last Updated

January 11, 2021

Record last verified: 2021-01

Data Sharing

IPD Sharing
Will not share

Locations