The Effect of Preoperative Values on Mortality in Patients Undergoing Open Heart Surgery
The Effect of Preoperative Neutrophil / Lymphocyte Ratio and Uric Acid Values on Short and Long Term Mortality in Patients Undergoing Open Heart Surgery
1 other identifier
observational
1,600
1 country
1
Brief Summary
Open heart surgeries are one of the major and complicated surgeries performed frequently in the world due to the prolongation of life expectancy and developments in medicine. As a result of these operations, not only the heart and vessels, but also all organs and systems depending on the systemic circulation are affected. Some biological inflammation markers have been determinant in determining cardiovascular risk. High neutrophil count was associated with increased mortality, while low lymphocyte count was a strong constant predictor of mortality. In addition, increased serum uric acid (UA) levels have been found to be associated with obesity, dyslipidemia, and hypertension, which is associated with cardiovascular disease risk. The aim of this study is to investigate the effects of patients who underwent coronary bypass surgery under elective conditions in Karadeniz Technical University Faculty of Medicine between 2008-2020 on in-hospital and 1-year mortality based on preoperative neutrophil / lymphocyte ratios and uric acid values.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Jun 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
June 1, 2020
CompletedFirst Submitted
Initial submission to the registry
February 2, 2021
CompletedFirst Posted
Study publicly available on registry
February 5, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 15, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
June 1, 2021
CompletedJune 21, 2021
June 1, 2021
9 months
February 2, 2021
June 18, 2021
Conditions
Keywords
Outcome Measures
Primary Outcomes (4)
neutrophil / lymphocyte ratios
The effect on postoperative complications of preoperative neutrophil lymphocyte ratio in open heart surgery
postoperative 2 week
neutrophil / lymphocyte ratios
The effect on mortality of preoperative neutrophil lymphocyte ratio in open heart surgery
postoperative 1 year
uric acid values
The effect on mortality of preoperative uric acid values in open heart surgery
postoperative 1 year
uric acid values
The effect on postoperative complications of preoperative uric acid values in open heart surgery
postoperative 2 week
Eligibility Criteria
This study was planned as a retrospective (retrospective) study involving patients who underwent elective open heart surgery between January 1, 2008 and December 31, 2020
You may qualify if:
- Elective patients undergoing open heart surgery
You may not qualify if:
- Immunodeficiency
- Emergency operations
- Patients whose records could not be accessed and who were excluded from the study group procedure in which they were included for any reason will not be included in the study.
- Patients under 18 years of age
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Karadeniz Technical University
Trabzon, 61080, Turkey (Türkiye)
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- assistant professor
Study Record Dates
First Submitted
February 2, 2021
First Posted
February 5, 2021
Study Start
June 1, 2020
Primary Completion
February 15, 2021
Study Completion
June 1, 2021
Last Updated
June 21, 2021
Record last verified: 2021-06