Modified Fraility Index in Patients Undergoing Arthroplasty

NCT05424575 | Completed

• 1 other identifier: AU I2-59-19
• Study Type: observational
• Target: 145
• Locations: 1 country
• Sites: 1

Brief Summary

The authors aimed to evaluate the relation between Modified Fraility Index (MFI) and postoperative complications (myocardial infarction, cardiac arrest, pulmonary embolism, septic shock, postoperative dialysis requirement, cerebrovascular event, reintubation, prolonged mechanical ventilation, surgical wound complications), duration of hospitalization, requirement for intensive care unit (ICU) admission and rehospitalization and 30th day mortality in patients undergoing arthroplasy.

Conditions

Frailty Syndrome; Postoperative Complications

Keywords

arthroplasty, fraility

Outcome Measures

Primary Outcomes (1)

• postoperative complications

  myocardial infarction, cardiac arrest, pulmonary embolism, septic shock, postoperative dialysis requirement, cerebrovascular event, reintubation, prolonged mechanical ventilation, surgical wound complications, duration of hospitalization, requirement for intensive care unit (ICU) admission and rehospitalization

  30 day

Secondary Outcomes (1)

• mortality

  30 day

Study Arms (2)

Group Nonfrail (Group NF)

Modified fraility index was calculated in all patients. Modified fraility index \< 0.27 were included to Group NF.

Group Frail (Group F)

Modified fraility index was calculated in all patients. Modified fraility index ≥ 0.27 were included to Group F.

Eligibility Criteria

• Age: 45 Years - 85 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

patients aged between 45-85 undergoing primary or revision total knee and hip arthroplasty

You may qualify if:

• patients aged between 45-85 undergoing primary or revision total knee and hip arthroplasty

You may not qualify if:

• Emergent surgery, patients aged below 45 and above 85, patients with cognitive dysfunction

Sponsors & Collaborators

• Ankara University: lead

Study Sites (1)

Ankara University Medical School Anesthesiology and ICU Department

Ankara, Turkey (Türkiye)

Location

Related Publications (1)

• Alibayli L, Cakar Turhan KS, Baytas V, Karadag Erkoc S, Bermede O, Kocaoglu H. Modified frailty index (mFI): is it a predictor for early postoperative complications in arthroplasty surgery? Eur Rev Med Pharmacol Sci. 2024 Feb;28(3):1002-1014. doi: 10.26355/eurrev_202402_35336.

  PMID: 38375705 DERIVED

MeSH Terms

Conditions

Frailty; Postoperative Complications

Condition Hierarchy (Ancestors)

Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Officials

• Sanem Cakar Turhan, Assoc. Prof.

  Ankara University Medical School Department of Anesthesiology and ICU

  STUDY CHAIR

• Leyla Alıbaylı, Specialist

  Ankara University Medical School Department of Anesthesiology and ICU

  PRINCIPAL INVESTIGATOR

• Volkan Baytas, Specialist

  Ankara University Medical School Department of Anesthesiology and ICU

  PRINCIPAL INVESTIGATOR

• Suheyla Karadag Erkoc, Specialist

  Ankara University Medical School Department of Anesthesiology and ICU

  PRINCIPAL INVESTIGATOR

• Onat Bermede, Specialist

  Ankara University Medical School Department of Anesthesiology and ICU

  PRINCIPAL INVESTIGATOR

• Hakan Kocaoglu, Assoc. Prof.

  Ankara University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof., MD

Study Record Dates

• First Submitted: June 15, 2022
• First Posted: June 21, 2022
• Study Start: July 20, 2020
• Primary Completion: October 20, 2020
• Study Completion: January 25, 2021
• Last Updated: June 21, 2022

Record last verified: 2022-06

Locations

TU (1)