Pulmonary Tuberculosis Sequelae in Patients With COPD

NCT04721080 | Unknown

• 1 other identifier: IKC145
• Study Type: observational
• Target: 150
• Locations: 1 country
• Sites: 1

Brief Summary

It is known that there is a complex relationship between tuberculosis and COPD. Post-tuberculosis airway disease or COPD associated with tuberculosis occurs in a significant portion of tuberculosis patients. However, it was observed that mortality rates and exacerbation rates of COPD patients with tuberculosis sequel were higher. However, the effect of tuberculosis sequela on functional outcomes in COPD patients has not been investigated in the studies. The aim of this study is to determine whether the previous tuberculosis sequelae has a functional effect on patients with COPD.

Conditions

Copd; Tuberculosis; Quality of Life

Keywords

copd; tuberculosis; exercise capacity; quality of life

Outcome Measures

Primary Outcomes (1)

• Exercise Capacity

  Six minutes walk test

  6 minutes- baseline

Secondary Outcomes (3)

• Dyspnea Assessment

  5 minutes- baseline

• COPD Assessment

  5 minutes- baseline

• Quality of Life Assessment

  20 minutes- baseline

Study Arms (2)

COPD patients with tuberculous sequelae

COPD patients with tuberculous sequelae

Other: Functional Outcome Measurements

COPD patients without tuberculosis sequela

COPD patients with tuberculous sequelae

Other: Functional Outcome Measurements

Interventions

Functional Outcome Measurements OTHER

Dyspnea Exercise capacity Quality of life assessment

COPD patients with tuberculous sequelae; COPD patients without tuberculosis sequela

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

COPD patients with tuberculous sequelae and COPD patients without tuberculosis sequela

You may qualify if:

• Volunteering to participate in the study
• Being over 18 years old
• Having thorax CT in the last 1 month
• Having PFT examination performed in the last 1 month

You may not qualify if:

• Being in a COPD attack
• The patient has additional pulmonary comorbidity such as Lung Ca, bronchiectasis, lung fibrosis.

Sponsors & Collaborators

• Izmir Katip Celebi University: lead

Study Sites (1)

İlknur Naz Gürşan

Izmir, 35620, Turkey (Türkiye)

RECRUITING

MeSH Terms

Conditions

Pulmonary Disease, Chronic Obstructive; Tuberculosis

Condition Hierarchy (Ancestors)

Lung Diseases, Obstructive; Lung Diseases; Respiratory Tract Diseases; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms; Mycobacterium Infections; Actinomycetales Infections; Gram-Positive Bacterial Infections; Bacterial Infections; Bacterial Infections and Mycoses; Infections

Study Officials

• Hulya Sahin

  Izmir Dr. Suat Seren Chest Diseases and Surgery Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Central Study Contacts

İlknur N Gürşan, Assoc Prof

CONTACT

05356954634; ilknurnaz4@gmail.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Year
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assoc. Prof

Study Record Dates

• First Submitted: January 19, 2021
• First Posted: January 22, 2021
• Study Start: May 1, 2020
• Primary Completion: May 1, 2021
• Study Completion: May 1, 2021
• Last Updated: March 3, 2021

Record last verified: 2021-02

Locations

TU (1)