Comparison of Salivary pH After Consuming Milk of Origin Vegetable vs Cow's Milk in Children

NCT04717778 | Completed

• 1 other identifier: 2019-100
• Study Type: interventional
• Target: 21
• Locations: 1 country
• Sites: 1

Brief Summary

The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female. They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk)

Conditions

pH

Outcome Measures

Primary Outcomes (2)

• Sociodemographic results

  The study was carried out in 21 first grade primary school children, 100% aged 6 years, 52.4% were female.

  1 hour the sociodemographic data of all the children were taken.

• pH results

  30 minutes after tooth brushing, each child was asked for the first saliva sample (basal pH measurement). After taking the basal pH, each child was given a glass with 50 ml of the milk to be measured. Saliva samples were measured with pH indicator strips and the result was recorded on custom charts. The pH was taken at 5, 10, 20, 30, 40 and 50 minutes. The normality distribution test (Shapiro-Wilk) was applied to the quantitative variables, with p = 0.0001, so that the data present a non-parametric or free distribution. To assess whether there were differences between the pH of the groups, the Kuskal-Wallis test was applied. For basal pH, p = 0.0001, therefore the null hypothesis is rejected and we conclude that the basal pH level is different in the five milks. Average basal pH: Rice milk 7 Cow milk 6.9 Almond milk 6.6 Soy milk 6.4 Coconut milk 6

  The average time of pH evaluation for each milk per child was an hour and a half.

Study Arms (1)

pH milk

EXPERIMENTAL

Group of children who were given the different types of milk and only the pH was measured

Dietary Supplement: Comparison of salivary pH after consuming milk of origin vegetable vs cow's milk

Interventions

Comparison of salivary pH after consuming milk of origin vegetable vs cow's milk DIETARY_SUPPLEMENT

They were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).

Also known as: cow´s milk, coconut milk, almond milk, soy milk and rice milk

pH milk

Eligibility Criteria

• Age: 3 Years - 6 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may qualify if:

• Boys and girls from 3 to 6 years

You may not qualify if:

• Boys and girls with allergies
• Children with lactose intolerance
• Elimination criteria:
• \- Boys and girls who do not want to participate at the time of the study

Sponsors & Collaborators

• Universidad Tecnologica de Mexico: lead

Study Sites (1)

UNITEC

Mexico City, 11320, Mexico

Location

Related Publications (3)

• Vanga SK, Raghavan V. How well do plant based alternatives fare nutritionally compared to cow's milk? J Food Sci Technol. 2018 Jan;55(1):10-20. doi: 10.1007/s13197-017-2915-y. Epub 2017 Nov 2.

  PMID: 29358791 BACKGROUND

• Hettinga K, van Valenberg H, de Vries S, Boeren S, van Hooijdonk T, van Arendonk J, Vervoort J. The host defense proteome of human and bovine milk. PLoS One. 2011 Apr 27;6(4):e19433. doi: 10.1371/journal.pone.0019433.

  PMID: 21556375 BACKGROUND

• Cuppari C, Manti S, Salpietro A, Dugo G, Gitto E, Arrigo T, Sturiale M, Salpietro C. ALMOND MILK: A POTENTIAL THERAPEUTIC WEAPON AGAINST COW'S MILK PROTEIN ALLERGY. J Biol Regul Homeost Agents. 2015 Apr-Jun;29(2 Suppl 1):8-12.

  PMID: 26634581 BACKGROUND

MeSH Terms

Interventions

Soy Milk

Intervention Hierarchy (Ancestors)

Milk Substitutes; Beverages; Diet, Food, and Nutrition; Physiological Phenomena; Soy Foods; Vegetable Products; Vegetables; Food; Food and Beverages

Study Officials

• Annia Avalos, Master

  Universidad Tecnológica Centroamericana

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: OTHER
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Model Details: The study was carried out in 21 first grade primary school children, they were given 5 types of milk, each one was measured on different days (Monday cow's milk, Tuesday coconut milk, Wednesday almond milk, Thursday soy milk, Friday rice milk).

Study Record Dates

• First Submitted: January 12, 2021
• First Posted: January 22, 2021
• Study Start: January 13, 2020
• Primary Completion: January 17, 2020
• Study Completion: January 17, 2020
• Last Updated: January 22, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will not share

Locations

ME (1)