The Impact of Anti- Asthmatic Medications on Salivary pH and Dental Caries Pattern in a Group of Egyptian Children With Bronchial Asthma

NCT03877874 | Unknown DMC FDA Drug

• 1 other identifier: 14422017495367
• Study Type: observational
• Target: 58
• Locations: 0 countries
• Sites: N/A

Brief Summary

The impact of Anti- Asthmatic medications on salivary pH and dental caries pattern in a Group of Egyptian Children with Bronchial Asthma.

Conditions

pH

Outcome Measures

Primary Outcomes (1)

• pH of Saliva

  Digital pH electrode meter

  1year

Secondary Outcomes (1)

• pattern of Dental caries

  1year

Other Outcomes (1)

• Drug composition(pH and total sugar content)

  2 minutes

Study Arms (2)

Asthmatic children

* Aironyl syrup(Terbutaline sulfate ................. 1.5mg) 0.075-0.29 mg/ kg body weight 3 times daily * Apidone syrup(Dexamethone) (0.02 to 0.3 mg per kilogram (kg) of body weight per day, divided and taken 3 or 4 times a day).

Drug: Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone)

Non-Asthmatic children

no intervention

Interventions

Aironyl syrup(Terbutaline sulfate) + Epidrone syrup(Dexamethone) DRUG

Aironyl syrup(Terbutaline sulfate ................. 1.5mg) 0.075-0.29 mg/ kg body weight 3 times daily Apidone syrup(Dexamethone) (0.02 to 0.3 mg per kilogram (kg) of body weight per day, divided and taken 3 or 4 times a day)

Asthmatic children

Eligibility Criteria

• Age: 6 Years - 12 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)
• Sampling Method: Probability Sample

Study Population

All patients presented to the Asthma and Allergy Outpatients Clinic of Abu El-Reesh Japanese hospital for kids will be included in the study according to the following criteria. -Control group: All patients attending the pediatric dentistry department of faculty of dentistry of Cairo University will be included in the study according to the following criteria.

You may qualify if:

• \- Children aged 6-12 years old diagnosed with Bronchial asthma (Mixed dentition stage).
• Control group : a matched group aged 6-12 years old
• Patients taking regular medications for the treatment of Bronchial asthma at least for 1 year back
• Both male and female patients will be included.

You may not qualify if:

• No other systemic Diseases.

Sponsors & Collaborators

• Cairo University: lead

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: March 12, 2019
• First Posted: March 18, 2019
• Study Start: July 1, 2021
• Primary Completion: September 1, 2021
• Study Completion: September 1, 2021
• Last Updated: February 1, 2021

Record last verified: 2021-01