NCT04716049

Brief Summary

The main objective of this project is to compare two recovery protocols, including nutritional and neuromuscular strategies on inmune, physiological and muscular responses.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Sep 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 12, 2021

Completed
8 days until next milestone

First Posted

Study publicly available on registry

January 20, 2021

Completed
8 months until next milestone

Study Start

First participant enrolled

September 3, 2021

Completed
3 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 6, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 6, 2021

Completed
Last Updated

September 16, 2021

Status Verified

September 1, 2021

Enrollment Period

3 days

First QC Date

January 12, 2021

Last Update Submit

September 8, 2021

Conditions

Keywords

performancerecoveryfatiguesoccer

Outcome Measures

Primary Outcomes (6)

  • Neuromuscular or physical performance measures change: jump height

    Counter Movement Jump (CMJ) will be performed to determine the maximum height in centimeters (cm). From standing position with the hands fixed on the hips, participants will be required to bend their knees to a freely chosen angle and perform a maximal vertical jump. Participants will be instructed to keep their body vertical throughout the jump, and to land with knees fully extended. Any jump that will be perceived to deviate from the required instructions will be repeated. Players will jump 3 times as high as possible and the average of the three jumps will be used in subsequent analysis. A 30-s passive recovery phase will be provided between jumps.

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Neuromuscular or physical performance measures change: maximal voluntary isometric contraction (MVIC)

    Isometric Hamstring Strength (IHS). Players will be in a supine position, with the tested leg strapped around the ankle (in a neutral position) and performed a hip extension (with a slight knee flexion 20º, while the non-dominant leg was resting on the floor). Players will place their hands on the wall to avoid sliding on the floor. A strain gauge will be placed between the ankle strap and the cord to evaluate the force (MVIC) exerted at a sampling frequency of 80Hz (Chronojump, Boscosystem®️, Barcelona, Spain). The tester will give all participants the same instructions; "to exert maximal force down to the floor" and continuous and standardized verbal motivation for 5 seconds. Each limb will be tested 3 times, in a randomized order. The assessment of both legs will be separated by 30 seconds while the time separating two trials of the same leg will be 60 seconds . The MVIC will be tested and measured in Newtons (N).

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Biochemical/Physiological measures change: creatine kinase

    Creatine Kinase (CK): units/L

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Biochemical/Physiological measures change: mioglobin

    Mioglobin: n/mol/L

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Biochemical/Physiological measures change: urea

    Urea: umol/L or mg/dL

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Biochemical/Physiological measures change: ions

    Na and K ions: mmol/L

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

Secondary Outcomes (7)

  • Range Of Movement (ROM) measures change: internal rotation of the hip

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Range Of Movement (ROM) measures change: ankle dorsiflexion degrees

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Range Of Movement (ROM) measures change: hamstrings extension ASLR

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Range Of Movement (ROM) measures change: hamstrings extension Jurdan

    Baseline, Immediately after intervention, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • Subjective perceptual/well-being questionnaire measures change: McLean

    Baseline, 24 hours after intervention, 48 hours after intervention, 72 hours after intervention

  • +2 more secondary outcomes

Study Arms (2)

Protocol I

EXPERIMENTAL

Powerade© Carbohydrates+Protein Cherry Juice Foam Roller Cold Water Immersion

Other: Powerade©, CHP, CJ, FR, CWI

Protocol II

EXPERIMENTAL

Powerade@ Carbohydrates+Protein Stretching Intermittent Cold-Water Immersion

Other: Powerade©, CHP, STR, ICWI

Interventions

Combination of recovery strategies including dietary, neuromuscular and physiological as follows: Powerade©: players will drink 500 mL during the game Carbohydrate and protein (CHP): players will drink 250 mL of water with CHP within 30 minutes after the end of the game. Tart cherry concentrate (CJ): players will drink 30 mL of CJ within 30 minutes after the end of the game. Foam roller (FR): players will follow FR protocol using a polyvinylchloride pipe roller. They will begin with the FR at the most proximal portion of the muscle and to roll as much body mass as tolerable back and forth at a cadence of 1 second superior and 1 second inferior for 45 seconds followed by a 15-second rest for each muscle group (quadriceps, adductors, hamstrings, abductors and calf) in each extremity and repeated once. Cold Water Immersion (CWI): will be the last strategy used. Players will immerse their lower body to the level of hips for 10 minutes in cold water (13-14°C).

Protocol I

Combination of recovery strategies including dietary, neuromuscular and physiological as follows: Powerade©: players will drink 500 mL of "Powerade©" during the game Carbohydrate and protein intake (CHP): players will drink 250 mL of water with CHP within 30 minutes after the end of the competition. Stretching (STR): players will perform 10-min of static stretching, involving 2 unilateral repetitions of 30 seconds held stretches to the quadriceps, adductors, hamstrings, abductors and calf muscles. Intermittent Cold-Water Immersion (ICWI): will be the last strategy used. It will consist of five 2 min intermittent immersions of the lower limb (up to the iliac crest) in a cold-water bath (13-14ºC), separated by 2 min rest in ambient air. Ice will be added to the bath at regular intervals to maintain water temperature at 13-14ºC. Players will be instructed to stand in the bath, with as little movement as possible.

Protocol II

Eligibility Criteria

Age18 Years+
Sexmale
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Elite young professional football players
  • minutes (at least) of game participation

You may not qualify if:

  • Goalkeepers
  • Injured players
  • Players unable to perform at their best
  • Players under medication

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Universitat de Vic-Universitat Central de Catalunya

Vic, Barcelona, 08500, Spain

Location

Related Publications (1)

  • McLean BD, Coutts AJ, Kelly V, McGuigan MR, Cormack SJ. Neuromuscular, endocrine, and perceptual fatigue responses during different length between-match microcycles in professional rugby league players. Int J Sports Physiol Perform. 2010 Sep;5(3):367-83. doi: 10.1123/ijspp.5.3.367.

MeSH Terms

Conditions

Fatigue

Interventions

somatostatin, cyclic hexapeptide(Phe-Phe-Trp-Lys-Thr-Phe)-

Condition Hierarchy (Ancestors)

Signs and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Albert Altarriba-Bartes

    UVic-UCC

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
OTHER
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 12, 2021

First Posted

January 20, 2021

Study Start

September 3, 2021

Primary Completion

September 6, 2021

Study Completion

September 6, 2021

Last Updated

September 16, 2021

Record last verified: 2021-09

Data Sharing

IPD Sharing
Will not share

Locations