Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults

NCT04938791 | Completed DMC

• 1 other identifier: ESSCVP_FIS01/2021
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic characteristics, level of activity and quality of life.

Conditions

Fatigue

Keywords

Respiration; Perceived; Kinematics; Performance

Outcome Measures

Primary Outcomes (10)

• Change from Baseline in perceived effort on the Borg category-ratio 10-point scale (CR 10)

  The perceived effort will be measured with Borg CR 10 scale. Possible scores range from 0 (no exertion at all) to 10 (extremely strong).

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in heart rate

  Heart rate (heart beatings per minute) measured before and during activity to track cardiovascular changes during activity.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in respiratory rate

  Respiratory rate (respiratory cycles per minute) measured before and during activity to track changes in respiratory function during activity.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in heart rate variability (HRV)

  Interval (in milliseconds) between consecutive heartbeats measured before and during activity to track changes in autonomic function during activity.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in electrodermal activity (EDA)

  Electrical conductance (in microsiemens -µS) between two points of the hand over time measured before and during activity to track changes in autonomic function during activity.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in muscle action potential amplitude through surface electromyography (sEMG)

  Muscle action potential amplitude (in millivolts - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in muscle action potential duration through surface electromyography (sEMG)

  Muscle action potential duration (in milliseconds - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in muscle action potential frequency through surface electromyography (sEMG)

  Muscle action potential frequency (in hertz - Hz) of surface electromyographic signal measured before and during activity to track muscular fatigue signs.

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in respiratory pattern through inertial motion units (IMU) from baseline and during activity

  Angular range of motion (in degrees) of rib cage and abdominal wall during upper limb activity measured before and during activity to track changes in respiratory pattern during activity

  From baseline to end of activity, up to 15 minutes

• Change from Baseline in upper limb motion angular acceleration through inertial motion units (IMU) system

  Angular acceleration (in m/s\^2) of the arm measured before and during activity to track small movements of upper limb during isometric activity

  From baseline to end of activity, up to 15 minutes

Secondary Outcomes (2)

• Health Status

  Before isometric activity

• Physical activity level

  Before isometric activity

Study Arms (1)

Isometric activity

EXPERIMENTAL

All participants will be included in this arm

Other: Isometric activity

Interventions

Isometric activity OTHER

Participants will do elevation of upper limbs and mantain a 90º degree flexion position in an unsupported way.

Also known as: Isometric task

Isometric activity

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Healthy
• Minimum age of 18 years;

You may not qualify if:

• Unable to provide written consent
• History of heart, cardiovascular and / or respiratory disease,
• Known untreated hypertension, cardiomyopathy, or exercise intolerance
• Presence of cognitive or neurological disorders
• Neuromuscular or orthopaedic disorder that limits the movement of the upper limb to 90° flexion or the maintenance of that position
• BMI ≥ 40

Sponsors & Collaborators

• Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa: lead

Study Sites (1)

Escola Superior de Saúde da Cruz Vermelha Portuguesa - Lisboa

Lisbon, 1300-125, Portugal

Location

Related Publications (1)

• Silva-Migueis H, Martinez-Jimenez EM, Casado-Hernandez I, Dias A, Monteiro AJ, Martins RB, Bernardes JM, Lopez-Lopez D, Gomez-Salgado J. Assessment and indicators of kinematic behavior and perceived fatigability. Rev Assoc Med Bras (1992). 2024 Feb 26;70(2):e20230924. doi: 10.1590/1806-9282.20230924. eCollection 2024.

  PMID: 38422320 DERIVED

MeSH Terms

Conditions

Fatigue; Respiratory Aspiration

Condition Hierarchy (Ancestors)

Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Respiration Disorders; Respiratory Tract Diseases; Pathologic Processes

Study Officials

• Daniel López López, PhD

  Universidade da Coruña

  STUDY DIRECTOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Senior Professor

Study Record Dates

• First Submitted: June 4, 2021
• First Posted: June 24, 2021
• Study Start: October 1, 2021
• Primary Completion: February 28, 2022
• Study Completion: February 28, 2022
• Last Updated: March 31, 2022

Record last verified: 2022-03

Data Sharing

• IPD Sharing: Will not share

Locations

PT (1)