The Quality of Recovery After General Anesthesia With Desflurane and Sevoflurane in Endoscopic Ureteral Lithotripsy

NCT04712162 | Completed

• 1 other identifier: 81/CN-HĐĐĐ
• Study Type: interventional
• Target: 60
• Locations: 1 country
• Sites: 1

Brief Summary

The good quality of recovery after general anesthesia is one of goals for short procedures and ambulatory surgeries. The study's objective was to compare the quality of recovery after general anesthesia with desflurane and sevoflurane with laryngeal mask airway for endoscopic ureteral lithotripsy.

Conditions

Anesthesia

Outcome Measures

Primary Outcomes (1)

• Time to awakening

  Time required for awakening

  After stopping volatile anesthetics to patient awakening, up to 30 minutes.

Secondary Outcomes (4)

• Time to wash-out of volatile anesthetics

  After stopping volatile anesthetics to complete wash-out of volatile anesthetics, up to 30 minutes

• Time to extubation

  After stopping volatile anesthetics to readiness for extubation, up to 30 minutes

• Irritation after awakening

  After awakening to eligible discharge, up to 2 hours.

• Adverse effects of volatile anesthetics

  After providing volatile anesthetics until they were stopped, up to 90 minutes

Study Arms (2)

D: maintain anesthesia with desflurane

OTHER

D: maintain anesthesia with Suprane® (Desflurane) at 6%. Volatile concentration was titrated according to end-tidal MAC to maintain 0.7-1.3 MAC using end-tidal monitor of Dräger Primus anesthesia machine.

Other: Other

S: maintain anesthesia with sevoflurane.

OTHER

S: maintain anesthesia with Sevorane® (Sevoflurane) at 2%. Volatile concentration was titrated according to end-tidal MAC to maintain 0.7-1.3 MAC using end-tidal monitor of Dräger Primus anesthesia machine.

Other: Other

Interventions

Other OTHER

Compare time to awakening and quality of recovery after general anesthesia between two groups.

D: maintain anesthesia with desflurane; S: maintain anesthesia with sevoflurane.

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• All eligible subjects who underwent endoscopic ureteral lithotripsy under general anesthesia
• ASA I and II

You may not qualify if:

• Contraindication to laryngeal mask airway.
• Indication for conversion to tracheal intubation during surgery.
• History of malignant hyperthermia.
• Pregnancy.
• Obese (BMI \>25 kg/m2).
• Substances abuse.

Sponsors & Collaborators

• Gia Dinh People Hospital: lead

Study Sites (1)

Anesthesiology Department of Gia Dinh People Hospital

Ho Chi Minh City, 700000, Vietnam

Location

Related Publications (21)

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Study Officials

• Thanh T. Nguyen, PhD

  Gia Dinh People Hospital

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: January 12, 2021
• First Posted: January 15, 2021
• Study Start: November 19, 2019
• Primary Completion: May 7, 2020
• Study Completion: May 7, 2020
• Last Updated: January 15, 2021

Record last verified: 2021-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, CSR, ANALYTIC CODE

Locations

VN (1)